Describe in conceptual detail how you could use genetic engineering to develop the vaccine BRV-PV. Note that rotavirus has a linear dsRNA genome with 11 segments coding for 12 proteins. Assume that you already have all of the necessary rotavirus genes cloned for use as starting materials.
Describe in conceptual detail how you could use genetic engineering to develop the vaccine BRV-PV...
BRV-PV is a live virus vaccine that replicates to some extent. How might you use genetic engineering to make a safer rotavirus vaccine? Note: the virus capsid is composed of 4 different proteins.
2. A dominant allele H reduces the number of body bristles that Drosophila flies have, giving rise to a “hairless” phenotype. In the homozygous condition, H is lethal. An independently assorting dominant allele S has no effect on bristle number except in the presence of H, in which case a single dose of S suppresses the hairless phenotype, thus restoring the "hairy" phenotype. However, S also is lethal in the homozygous (S/S) condition. What ratio of hairy to hairless flies...
Refer to the assigned article “In a Bean, a Boon to Biotech” (Pictures of article are underneath). 1A. (200 words or less) The article states “Both Monsanto’s Vistive Gold soybeans and DuPont Pioneer’s Plenish soybeans are engineered to silence the gene for an enzyme that converts oleic fatty acid into linoleic acid.” These products were developed 10 years ago. Describe in conceptual detail : 1) how the gene silenced soybean was likely produced (100 words). 2) how the gene silenced...
How can we assess whether a project is a success or a failure? This case presents two phases of a large business transformation project involving the implementation of an ERP system with the aim of creating an integrated company. The case illustrates some of the challenges associated with integration. It also presents the obstacles facing companies that undertake projects involving large information technology projects. Bombardier and Its Environment Joseph-Armand Bombardier was 15 years old when he built his first snowmobile...