Show all steps for the synthesis of aspirin (acetylsalicylic acid)
Hint: Esterification
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Show all steps for the synthesis of aspirin (acetylsalicylic acid) Hint: Esterification
Experiment 2: Synthesis of Aspirin (Acetylsalicylic Acid ) 1. How many moles of salicylic acid are...
Experiment 2: Synthesis of Aspirin (Acetylsalicylic Acid ) 1. How many moles of salicylic acid are there in 1.0 grams of salicylic acid? 2. How many moles of acetic anhydride are there in 3 mL of acetic anhydride? 3. When 1.0g of salicylic acid and 3 mL of acetic anhydride react, DETERMINE which one is the limiting reactant (you can go to General Chemistry if you need help about limiting reagent)? 4. What is phosphoric acid used for in the...
H3PO4 OH + OH OH salicylic acid acetic anhydride acetic acid acetylsalicylic acid (aspirin) 1. Why...
H3PO4 OH + OH OH salicylic acid acetic anhydride acetic acid acetylsalicylic acid (aspirin) 1. Why is it better to perform acetylation with acetic anhydride rather than using a Fischer esterification with acetic acid? 2. Draw a complete arrow-pushing mechanism for the reaction. 3. When an old sample of aspirin is left in moist conditions, it will begin to smell like vinegar. Draw a reaction scheme and briefly explain what happened.
Aspirin was prepared from salicylic acid by ...... O esterification of the acetic anhydride O esterification...
Aspirin was prepared from salicylic acid by ...... O esterification of the acetic anhydride O esterification of the concentrated sulfuric acid O acetylation of concentrated sulfuric acid O esterification of the carboxylic group O acetylation of the phenolic group
please help Mustrates treat all types of ilnesses. Background Aspirin is a prodrug of salicylic acid,...
please help
Mustrates treat all types of ilnesses. Background Aspirin is a prodrug of salicylic acid, the actual active drug. A compound related to salicylic acid, salicin, was first isolated from willow bark in the mid 1700's, but willow-bark extract was used by the andient Greeks as a treatment for pain and fever. Salicylic acid (and many related phenols) are very hard on your Ho stomach, but when esterified, as aspirin is, they are much better tolerated. Simple esters are...
10) A student prepares aspirin (acetylsalicylic acid, C,H,0.) by reacting salicylic acid (C,H,O,) with acetic anhydride...
10) A student prepares aspirin (acetylsalicylic acid, C,H,0.) by reacting salicylic acid (C,H,O,) with acetic anhydride (C.H.O.). The balanced equation for the reaction is: 2 C,H,O, + C,H,O, + 2 C,H,O, + H,O The lab calls for 3.00 g of salicylic acid to be mixed with 6.40 g of acetic anhydride. What is the limiting reagent and what is the maximum amount of aspirin which can be prepared if the yield for the reaction is 91%?
PRELAB EXERCISE EXPERIMENT 21 Synthesis of Aspirin (Acetylsalicylic Acid) 1. What is the purpose of sulfuric...
PRELAB EXERCISE EXPERIMENT 21 Synthesis of Aspirin (Acetylsalicylic Acid) What is the purpose of sulfuric acid or phosphoric acid used in the acetylation reaction? Use equations to explain this purpose. The procedure calls for cautious addition of water to the reaction mixture while it is still hot. What purpose does the addition of water serve and why should the addition be done while the reaction mixture is hot? Provide an equation for the reaction involved.Using the quantities of salicylic acid and acetic anhydride...
95 Experiment IX Synthesis of Aspirin Prelaboratory Assignment Name: frobect Bun, Bak Baniot Date...
95 Experiment IX Synthesis of Aspirin Prelaboratory Assignment Name: frobect Bun, Bak Baniot Date Sabaitecd Section #. . Using chemical structures, write the balanced equation for the synthesis of aspirin and label all reagents and products with their appropriate names. ooH он C14 14,03 2. What are the two functional groups on salicylic acid? 3. What are the two functional groups on aspirin? b. anhydride? b) How many moles of Apririn could be produced from 2 moles of salicylic acid?...
1) Which reactant, salicylic acid or acetic anhydride, is in excess? Show your work. 2) If you we...
1) Which reactant, salicylic acid or acetic anhydride, is in
excess? Show your work.
2) If you were to use 3.17 g of starting material, how much
product would you expect? Again, show your work.
3) Why is phosphoric acid added to the reaction?
4) A small amount of water is added at the end of the reaction
to react with the excess acetic anhydride. Show a balanced equation
for that reaction.
5) Explain the purpose of the FeCl3 test...
find the theoretical yield of the acetysalicylic acid . EXPERIMENT 19 PREPARATION OF ASPIRIN In addition...
find the theoretical yield of the acetysalicylic acid .
EXPERIMENT 19 PREPARATION OF ASPIRIN In addition to the Fischer esterification method presented in Experiment 18, a second method for preparation of esters involves the reaction of anhydrides with the hydroxyl This method is ospecialy usoful for tho preparation of acetate esters, since acetic anhydride is an inexpensive and reactive reagent. In this experiment the hydroxyl group of salicylic acid is acetic anhydride to make acetylsalicylic acid, or aspirin. The short...
Acetylsalicylic acid (aspirin) can be synthesized from salicylic acid and acetic acid in an acidic solution....
Acetylsalicylic acid (aspirin) can be synthesized from salicylic acid and acetic acid in an acidic solution. COOH COOH Сн,соон на + H20 H HC. O-H salicylic acid acetylsalicylic acid (aspirin) We were unable to transcribe this image
H3PO4 OH + OH OH salicylic acid acetic anhydride acetic acid acetylsalicylic acid (aspirin) 1. Why is it better to perform acetylation with acetic anhydride rather than using a Fischer esterification with acetic acid? 2. Draw a complete arrow-pushing mechanism for the reaction. 3. When an old sample of aspirin is left in moist conditions, it will begin to smell like vinegar. Draw a reaction scheme and briefly explain what happened.
Aspirin was prepared from salicylic acid by ...... O esterification of the acetic anhydride O esterification of the concentrated sulfuric acid O acetylation of concentrated sulfuric acid O esterification of the carboxylic group O acetylation of the phenolic group
please help
Mustrates treat all types of ilnesses. Background Aspirin is a prodrug of salicylic acid, the actual active drug. A compound related to salicylic acid, salicin, was first isolated from willow bark in the mid 1700's, but willow-bark extract was used by the andient Greeks as a treatment for pain and fever. Salicylic acid (and many related phenols) are very hard on your Ho stomach, but when esterified, as aspirin is, they are much better tolerated. Simple esters are...
10) A student prepares aspirin (acetylsalicylic acid, C,H,0.) by reacting salicylic acid (C,H,O,) with acetic anhydride (C.H.O.). The balanced equation for the reaction is: 2 C,H,O, + C,H,O, + 2 C,H,O, + H,O The lab calls for 3.00 g of salicylic acid to be mixed with 6.40 g of acetic anhydride. What is the limiting reagent and what is the maximum amount of aspirin which can be prepared if the yield for the reaction is 91%?
PRELAB EXERCISE EXPERIMENT 21 Synthesis of Aspirin (Acetylsalicylic Acid) What is the purpose of sulfuric acid or phosphoric acid used in the acetylation reaction? Use equations to explain this purpose. The procedure calls for cautious addition of water to the reaction mixture while it is still hot. What purpose does the addition of water serve and why should the addition be done while the reaction mixture is hot? Provide an equation for the reaction involved.Using the quantities of salicylic acid and acetic anhydride...
95 Experiment IX Synthesis of Aspirin Prelaboratory Assignment Name: frobect Bun, Bak Baniot Date Sabaitecd Section #. . Using chemical structures, write the balanced equation for the synthesis of aspirin and label all reagents and products with their appropriate names. ooH он C14 14,03 2. What are the two functional groups on salicylic acid? 3. What are the two functional groups on aspirin? b. anhydride? b) How many moles of Apririn could be produced from 2 moles of salicylic acid?...
1) Which reactant, salicylic acid or acetic anhydride, is in
excess? Show your work.
2) If you were to use 3.17 g of starting material, how much
product would you expect? Again, show your work.
3) Why is phosphoric acid added to the reaction?
4) A small amount of water is added at the end of the reaction
to react with the excess acetic anhydride. Show a balanced equation
for that reaction.
5) Explain the purpose of the FeCl3 test...
find the theoretical yield of the acetysalicylic acid .
EXPERIMENT 19 PREPARATION OF ASPIRIN In addition to the Fischer esterification method presented in Experiment 18, a second method for preparation of esters involves the reaction of anhydrides with the hydroxyl This method is ospecialy usoful for tho preparation of acetate esters, since acetic anhydride is an inexpensive and reactive reagent. In this experiment the hydroxyl group of salicylic acid is acetic anhydride to make acetylsalicylic acid, or aspirin. The short...
Acetylsalicylic acid (aspirin) can be synthesized from salicylic acid and acetic acid in an acidic solution. COOH COOH Сн,соон на + H20 H HC. O-H salicylic acid acetylsalicylic acid (aspirin) We were unable to transcribe this image
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