. If an adenoviral vector is used for gene therapy, why might it be necessary to give the patient...
. If an adenoviral vector is used for gene therapy, why might it be necessary to give
the patient multiple rounds?
4. How can a “suicide gene” be used to treat cancer?
5. Rexin-G is an effective vector for tumor treatment. Describe its 2 primary modes of
action.
Homework Answers
To access sustainable gene expression, multiple rounds of adenoviral vector is used.
4) In suicide gene therapy their is introduction of viral or bacterial genes into tumors cells, which in turn convert a non-toxic pro-drug to a toxic one, and results in killing of Cancer cells.
5) Rexin-G has been shown effectively shrinking of metastatic tumours and triples the survival times of chemotherapy-resistant cancers.
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1.
2. Why did Billy's diarrhea improve when he was being prepared
for transplantation?
3. Intravenous immunoglobulin has been used to treat IPEX . How
might that be an effective therapy?
4. The occurrence of colitis in IPEX suggests that Treg cells
may be implicated in it's parthenogenesis and that might be used
therapeutically in more common forms of colitis. Is there
experimental data to support this claim?
5. What other gene mutations can be give rise to a clinical...
1. Why is iPS cell therapy using third-party donor cells more feasible than using cells donated from the patient being treated? O Treatment with iPS cells is much more cost prohibitive when iPS cells are donated by the patient being treated. O Donor iPS cells from the patient cannot be used because they contain the disease being treated. O Third-party donor cells are less likely to contain dangerous mutations that can lead to tumor formation. O Third-party donors are screened...
5-10
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