Homework Answers
1)
Cold temperatures decrease the solubility of the acetaminophen, causing more of the product to "fall out" of solution
2)
In the reaction of acetaminophen synthesis, 0.450 L of water is added.It serves to hydrolyze the acetic anhydride to promote peptide bond formation with p-aminophenol.
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Synthesis of Acetaminophen Postlab Questions During the crystallization of acetaminophen, why was...
What is the theoretical yield of acetaminophen in an experiment that combines 1.5g of p-aminophenol, 25mL...
What is the theoretical yield of acetaminophen in an experiment that combines 1.5g of p-aminophenol, 25mL of water, 20 drops of concentrated phosphoric acid, and 2 mL of acetic anhydride. And recrystallization of acetaminophen that involved adding 20mL of water with the crude acetaminophen crystals. Please include work.
Explain what is the purpose of the following reagents/procedural steps in the synthesis of acetaminophen by...
Explain what is the purpose of the following reagents/procedural steps in the synthesis of acetaminophen by reacting p-aminophenol with acetic anhydride: a. Phosphoric acid b. Placing the reaction flask in warm water c. Purpose for placing crude product of acetaminophen in a 100 ml beaker with 20 ml of water, then heat it on a hot plate until crystals dissolves then let cool. Then having it in an ice bath for 20 min once crystals appeared. d. Drying product at...
Place 3.0 g of salicylic acid in a 125-ml Erlenmeyer flask. Carefully add, stirring constantly, 6...
Place 3.0 g of salicylic acid in a 125-ml Erlenmeyer flask. Carefully add, stirring constantly, 6 mL of acetic anhydride, followed by 10 drops of concentrated sulfuric acid. Swirl the contents of the flask so that the reactants are thoroughly mixed. Stopper the flask with a one- hole cork fitted with an inverted Pasteur pipet to prevent condensation of water in the reaction flask during heating on the steam bath. Heat the flask in a boiling-water or steam bath for...
this is the procedure of melting point experiment ( preparation acetanilid) I want the summarize of...
this is the procedure of melting point experiment
( preparation acetanilid) I want the summarize of this
procedure
EXPERIMENTAL PROCEDURE Measure 0.100 to 0.125 g of aniline (in dropper bottles near the balances) into a tared reaction tube from the microscale kit and record the weight to the nearest milligram. Add 2 mL of distilled water and 6 to 7 drops (an excess amount, 21 drops =1 mL) of acetic anhydride. Stir the mixture for about 4 minutes untiha solid...
If you were to run this reaction on a 0.5 g acetaminophen, how much powdered potassium...
If you were to run this reaction on a 0.5 g acetaminophen, how
much powdered potassium carbonate would you use ? Show your
work
Alcohols and Ethers 185 14.3 THE WILLIAMSON ETHER SYNTHESIS: PREPARATION OF PHENACETIN FROM ACETAMINOPHEN One of the most common methods used to prepare ether Williamson ether synthesis. In this reaction, an alkoxide anion (RO) acts as a nucleophile in an S, 2 process, displacing a leaving group (X) from an electrophile (R-X). R-20 . RY ROR...
using pictures and a maximum of 10 words, explain why an oven-dried 5-ml conical vial and...
using pictures and a maximum of 10 words, explain why an oven-dried
5-ml conical vial and drying tube(step 1 and 2 of part 1) are used
in the reaction. do both please! also the notebook pages are the
procedure
(1) Using pictures and a maximum of 10 words, explain why an oven-dried 5-ml conical vial and drying tube (step 1 and 2 of Part 1) are used in the reaction. (2) After the addition of benzophenone to the mixture of...
Find %yield please the product obtained was 0.0870g In the hood, place 100 mu L of...
Find %yield please the product obtained was 0.0870g
In the hood, place 100 mu L of aniline in a tared 10 times 75 mm (small) test tube. Place the test cube in a small beaker or Erlenmeyer flask to avoid spillage. Stopper the cube with a cork. Now, using a Pasteur pipet, add (with swirling) 0.5 mL of water, followed by three drops of concentrated HCI. Add 10 mg of decolorizing charcoal (we use the pelletized form, called Nonrit^TM) to...
Can someone tell me if a theoretical yield needs to be calculated for this experiment? And...
Can someone tell me if a theoretical yield needs to be
calculated for this experiment? And if so, how do you calculate it?
please show all work. thank you. btw the aniline weighs
6.69g.
Synthesis of Acetanilide Acetanilide is synthesized from aniline by a reaction known as acylation. Acylation is the addition of an acyl group to a compound. In this experiment, aniline (1 amine) is reacted with acetic anhydride (acylating agent) to form acetanilide (an amide). H-C-CH3 + CH...
i did the synthesis of aspirin experiment and got the data below. how do you do...
i did the synthesis of aspirin experiment and got the data
below. how do you do the theoretical yield? percent yield of the
pure aspirin?
DATA: Mass of Salicylic Acid: 2.034g Volume of Acetic Anhydride used in synthesis: 4.00ml Mass of filter paper: 0.196g Mass of filter paper plus Aspirin: 1.868g Mass of Aspirin: 1.672g Percent Yield of Pure Aspirin: I Experimental Procedure HAZARD: Sulfuric acid, acetic anhydride and glacial acetic acid are corrosive to the skin. They are also...
Question- The second step is a name reaction. a) What is its name: b) Is it...
Question- The second step is a name reaction. a) What is its name: b) Is it OK that we left the reaction in our drawer over the week? What would have happened if we didn’t have a good seal on the stopper? Draw a possible reaction scheme. Background The field of medicinal chemistry combines the specialties of synthetic organic chemistry and biology, and biochemistry. Compounds are generated and biological activity is screened using target specific assays. . These assays are...
Place 3.0 g of salicylic acid in a 125-ml Erlenmeyer flask. Carefully add, stirring constantly, 6 mL of acetic anhydride, followed by 10 drops of concentrated sulfuric acid. Swirl the contents of the flask so that the reactants are thoroughly mixed. Stopper the flask with a one- hole cork fitted with an inverted Pasteur pipet to prevent condensation of water in the reaction flask during heating on the steam bath. Heat the flask in a boiling-water or steam bath for...
this is the procedure of melting point experiment
( preparation acetanilid) I want the summarize of this
procedure
EXPERIMENTAL PROCEDURE Measure 0.100 to 0.125 g of aniline (in dropper bottles near the balances) into a tared reaction tube from the microscale kit and record the weight to the nearest milligram. Add 2 mL of distilled water and 6 to 7 drops (an excess amount, 21 drops =1 mL) of acetic anhydride. Stir the mixture for about 4 minutes untiha solid...
If you were to run this reaction on a 0.5 g acetaminophen, how
much powdered potassium carbonate would you use ? Show your
work
Alcohols and Ethers 185 14.3 THE WILLIAMSON ETHER SYNTHESIS: PREPARATION OF PHENACETIN FROM ACETAMINOPHEN One of the most common methods used to prepare ether Williamson ether synthesis. In this reaction, an alkoxide anion (RO) acts as a nucleophile in an S, 2 process, displacing a leaving group (X) from an electrophile (R-X). R-20 . RY ROR...
using pictures and a maximum of 10 words, explain why an oven-dried
5-ml conical vial and drying tube(step 1 and 2 of part 1) are used
in the reaction. do both please! also the notebook pages are the
procedure
(1) Using pictures and a maximum of 10 words, explain why an oven-dried 5-ml conical vial and drying tube (step 1 and 2 of Part 1) are used in the reaction. (2) After the addition of benzophenone to the mixture of...
Find %yield please the product obtained was 0.0870g
In the hood, place 100 mu L of aniline in a tared 10 times 75 mm (small) test tube. Place the test cube in a small beaker or Erlenmeyer flask to avoid spillage. Stopper the cube with a cork. Now, using a Pasteur pipet, add (with swirling) 0.5 mL of water, followed by three drops of concentrated HCI. Add 10 mg of decolorizing charcoal (we use the pelletized form, called Nonrit^TM) to...
Can someone tell me if a theoretical yield needs to be
calculated for this experiment? And if so, how do you calculate it?
please show all work. thank you. btw the aniline weighs
6.69g.
Synthesis of Acetanilide Acetanilide is synthesized from aniline by a reaction known as acylation. Acylation is the addition of an acyl group to a compound. In this experiment, aniline (1 amine) is reacted with acetic anhydride (acylating agent) to form acetanilide (an amide). H-C-CH3 + CH...
i did the synthesis of aspirin experiment and got the data
below. how do you do the theoretical yield? percent yield of the
pure aspirin?
DATA: Mass of Salicylic Acid: 2.034g Volume of Acetic Anhydride used in synthesis: 4.00ml Mass of filter paper: 0.196g Mass of filter paper plus Aspirin: 1.868g Mass of Aspirin: 1.672g Percent Yield of Pure Aspirin: I Experimental Procedure HAZARD: Sulfuric acid, acetic anhydride and glacial acetic acid are corrosive to the skin. They are also...
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