a. draw the major form of your drug (wellbutrin) when pH is low (acidic medium) for all acid-base groups draw the major form of drug when pH is high (basic medium) for all acid-base groups.
What is the major form for each acidic group of histidine when the pH of the solution is 7.00? A. Carboxylic acid; imidazolium; ammonium B. Carboxylate; imidazole; ammonium C. Carboxylate; imidazolium; ammonia D. Carboxylate; imidazolium; ammonium I know its not A or B
Titrate an amino acid that isn’t acidic or basic and also doesn’t have a titratable group on its R that will be ionized starting from ph 1-14 with the ionization of the side groups. When will they lose their protons, what are the weak acid of the carboxyl and discuss the titration of the carboxyl and amino groups. Illistrate the two charged groups on the amino acid at neutral, acidic and basic pH. whats the pH of charged groups when...
Show all work and steps please 24 Phenolphthalein is a commonly used indicator that is colorless in the acidic form (pH less than 8 3) and pink in the base form (pH greater than 100) It is a weak acid with a pka of 8.7. What fraction is in the acid form when the ocid color is apparent? What fraction is in the base form when the base color is apparent? 24 Phenolphthalein is a commonly used indicator that is...
Draw a structural formula for the major ionic form of the amino acid shown below when in aqueous solution at pH 11.0. H2NCCH2CH2CHCoH t NH3 glutamine Draw a structural formula for the major ionic form of the amino acid shown below when in aqueous solution at pH 11.0. H2NCCH2CH2CHCoH t NH3 glutamine
1. a. Draw the pH curve for a strong acid and a weak acid when a strong base is added. Note the in the case of the weak acid, the addition of the strong base yields a common ion (i.e conjugate base) when it is dissolved. b. Explain the difference between the two curves. (Hint: why is one curve showing a very small change in pH along y-axis in the acidic region when the strong base is added?
46. Most enzymes function best at a. acidic pH and high salt concentrations b. basic pH and low salt concentrations c. neutral pH and high salt concentrations d. around pH 7 and low salt concentrations 47. Which of the following cells contain respiratory enzymes contained in an internal structure surrounded by membranes? a. plant cells b. Mycobacterium tuberculosis cells c. animal cells d. S. aureus cells e. a &c
C. Explain about solubility of an amino acid when subjected to an acidic media and basic media. Indicate the compound which would be at the isoelectric point. (Draw a diagram to help explain) c. Explain about the solubility of and amino acid when subjected to an acidic media and basic media. Indicate the compound which would be at the isoelectric point. (Draw a diagram to help explain). (3 marks) Amino acids are the building blocks of proteins, acidic amino acids...
Identify the functional groups Find H-bond donors and acceptors Identify any acidic or basic groups and draw the compound at various pHs using the pKa tables Calculate the solubility Identify potential molecular interactions that are possible when the drug binds to its target. If the pharmacophore for this drug includes the propanolamine and the aryl ring, propose an isosteric modification that will still produce an active drug. Simplify the drug, yet still produce an active drug Propose a modification that...
1) Fosamax has six acidic groups. The structure of the active form of the drug is shown in the figure below. (Notice that the phosphorus atom in Fosamax can be surrounded by more than eight electrons since P is below the second row of the periodic table.) A)The OH groups bonded to phosphorus are the strongest acids of the six groups. Why? a) Because phosphorus atom is less electronegative rather than atoms bonded to other acidic groups. b) Because the...
update: this is all that is given 1. Given the following acid-base equilibria, indicate the major component or components at each pH. + H3N OH H3N H2N. NH NH NH рКа; = 2.38 [C] pka = 9.39 [Z] [A] pl = 5.88 a. pH = 2.38 b. pH = 5.88 C. pH = 11 2. Rank the following compounds from most acidic to least acidic. HEN H3N H2N ОН H2N ОН NH3 - II III