FIVE. You have identified a new mutant in Drosophila that
defines a gene you call “red.” When mutant
it causes the “neck” of the fly (cervical connective) to be red. It
behaves as an autosomal recessive
mutation with alleles red+ and red-.
You suspect it is linked to two known genes on the second
chromosome “re” and “ti”. The re-
mutation behaves as an autosomal recessive. Homozygous mutant flies
fixate on TV reruns, “re+”
normal flies avoid TV. The “ti” gene is linked to the “re” gene and
also behaves as an autosomal
recessive. Homozygous mutant flies are attracted to ti leaves,
“ti+” flies are not.
You crossed homozygous “red-“ flies to “re- ti-“ flies. The F1 are
all normal in phenotype; F1 flies are
then crossed to the triply homozygous mutant “red- re- ti-“ stock.
The following F2 are recovered (the
“red” gene is assumed to be in the middle of the linkage group,
that may not be true).
Phenotype Number
“re+ red- ti+” 4735
“re- red+ ti-“ 4716
“re+ red+ ti-“ 254
“re- red- ti+” 245
“re+ red+ ti+” 25
“re- red- ti-“ 24
“re- red+ ti+ 1
(Note, only 7 classes were recovered). Does your new gene form a
linkage group with the known
genes? If so, provide the map with map distances. Is there any
interference? If so, how much?
FIVE. You have identified a new mutant in Drosophila that defines a gene you call “red.” When mutant it causes the “neck” of the fly (cervical connective) to be red. It behaves as an autosomal recessi...
You have discovered a new mutation in Drosophila that causes the flies to have leg tremors. You name the mutation shaker (sh), and determine that it is an autosomal recessive mutation. You want to determine whether the sh gene is linked to the recessive mutation causing loss of wings (apterous, ap). You cross a fly heterozygous for sh and ap with a fly homozygous for both sh and ap, and obtain the following results: sh+ ap+ 321 flies sh ap...
Researchers have identified a gene in humans that (when mutant) causes severe dwarfism and mental retardation. This disorder is inherited in an autosomal recessive manner, and the mutant allele is known to be a loss-of-function mutation. The same gene has been found on mice, although a mutant version of the gene has not been discovered in mice. To develop drugs and an effective therapy to treat this disorder, it would be extremely useful to have a mouse model of the...
the fruit fly, Drosophila melanogaster, an allele (v) of the gene vermillion gives flies purple eyes and is recessive to the wildtype red eye color (v+). An allele y of the yellow gene, gives flies a yellow body color compared to the dominant brown body color (yt). A heterozygous females for the two different mutations is test-crossed with mutant (i.e., homozygous recessive) males. The phenotypes of the progeny of this cross and their corresponding numbers are given below Yellow body,...
Suppose that a geneticist discovers a new mutation in Drosophila melanogaster that causes the flies to shake and quiver. She calls this mutation quiver, qu, and determines that it is due to an autosomal recessive gene. She wants to determine whether the gene encoding quiver is linked to the recessive gene for vestigial wings, vg. She crosses a fly homozygous for quiver and vestigial traits with a fly homozygous for the wild-type traits, and then uses the resulting F1 females...
5.) You have discovered mutants in two new gene mutants in Drosophila. One mutant, curl, has small, curly, nonfunctional wings. The other mutant, big, has enormous eyes. You decide to test if these two new genes are on chromosome #2, so you perform a three-gene linkage testcross using a gene that you know is on chromosome #2, trp, a mutant that cannot make its own tryptophan (and so must get it from its food). In all three cases, these mutant...
please help me!!! 5.) You have discovered mutants in two new gene mutants in Drosophila. One mutant, curl, has small, curly, nonfunctional wings. The other mutant, big, has enormous eyes. You decide to test if these two new genes are on chromosome #2, so you perform a three-gene linkage testcross using a gene that you know is on chromosome #2, trp, a mutant that cannot make its own tryptophan (and so must get it from its food). In all three...