Question

D Question 9 0.59 pts 2 mM ATP 5 3- C21 nM AMPK-AMP Kinase Which of the following best explains what is happening in this graph? e There is a negative correlation between substrate concentration and AMPK activity. ATP acts as an allosteric activator when concentration of substrate is at least 10 nM. AMPK is not active without the presence of the substrate at 10 nM or greater concentration.

Answer 1

AMPK is not active without the presence of substrate at 10nM or greater. This is because of the presence of ATP, in  2mM, when the substrate concentration is 1nM does not have any effect on the activity of AMPK.