Predict the major product for the following reaction (CH3)3CCH2Cl AICl3 CH2C(CH3)3 C(CH3)2CH2CH3 CH(CH3)CH2CH2CH3 сњ...
For each reaction predict the product. If isomers are possible only show the major product. H3C Br SO3 H2SO4 ("fuming') AICI HNO3 a) c) H3C H2SO4 Cl d) CH3 (internal F-C AICl3 alkylation) H3C
833 17-10 The Friedel-Crafts Alkylation 1.2NaOH 100 °C 2. H,09 o Zn(Hg) dilute HCI NBS hy NO, Zn HCI C 17-10 The Friedel-Crafts Alkylation U 8. Predict the major product or products for the following reactions. Assume reagents are present in excess amounts unless otherwise indicated. Clearly depict any stereochemistry. "No Reaction is a possible answer. (4 points) each et :O 1 SO, H2SO4 CH2 CH3 сH,CH,CI AICI, NO2 Br FeBrz OH AICI 1 cq Bry FeBr
Draw the major organic product of the following Friedel–Crafts alkylation. (An excess of benzene is present.) Do not draw any aluminum byproducts. Draw the major organic product of the following Friedel- Crafts alkylation. (An excess of benzene is present.) Do not draw any aluminum byproducts CI AlCl
PLEASE ANSWER ALL QUESTIONS 41) Provide the major organic product of the following reaction. Bry, FeBry 42) Provide the major organic product that results when benzene is treated with the following sequence of reagents: 1. HNO3, H2SO4 2. Br2, FeBr3. Answer: NO2 43) Explain why Friedel-Crafts alkylation reactions are prone to poly alkylation, whereas Friedel- Crafts acylation reactions are not prone to polyacylation? 44) Which series of reagents would be required to perform the following synthesis? A) 1. CICH2CH2CH3, AICI;...
Draw the major organic product of the following Friedel–Crafts alkylation. (An excess of benzene is present.) aw the major organic product of the following Friedel-Crafts alkylation. (An excess of benzene is present.) AICI, Previous ⓧ Give Up & View Solution # Try Again Next Exit Explanation This reaction is an electrophilic aromatic substitution. The aluminum chloride polarizes the chlorine-carbon bond of the alkyl halide, imparting carbocation character (i.e., electrophilicity) to the alkyl group Since an excess of benzene is present,...
Give the major product for the following reaction. OH H2Cro4 H2SO4 H20 CH:0—C—CH2CH2CH3 CH:—C—0CH,CHCH: CH:0— —OCH2CH2CH3 CH—9—CH,CH, CH3 O CH—¢-CH2CH2CH3 OH
Predict the major product of the following reaction: HN AICl3 CI NH HN HN HN O A O B O C O D O E no reaction
Draw the major organic product for the following Friedel-Crafts acylation reaction: (CH3)3CCOC? FeCl
The major product of the following reaction is: CH3CHCH2CH2Br CH3CH2S- Na DMSO CH CH2C=CHCH CH3CHCH=CH2 CH3CHCH2CHSCH CH3 CH3 CH3 CH3 Til OA O B. III oc there is no major product D. I and II OE. II
Write a structural formula for the product from Friedel-Crafts alkylation or acylation of benzene for each compound: CI olar a) b) Complete these electrophilic aromatic substitution reactions. Br SOZH heat + H2SO4 b) HNO3 H2SO4 Predict the major product of each electrophilic aromatic substitution OH OH NO2 Br2 b) NO2 SOZ H2SO4 CH3 c) Br2 AICI: SO3H