Question

PLEASE ANSWER ALL QUESTIONS

41) Provide the major organic product of the following reaction. Bry, FeBry 42) Provide the major organic product that results when benzene is treated with the following sequence of reagents: 1. HNO3, H2SO4 2. Br2, FeBr3. Answer: NO2 43) Explain why Friedel-Crafts alkylation reactions are prone to poly alkylation, whereas Friedel- Crafts acylation reactions are not prone to polyacylation? 44) Which series of reagents would be required to perform the following synthesis? A) 1. CICH2CH2CH3, AICI; B) 1. CICOCH2CH3, AlCl3 C) 1. CICOCH2CH3, AICI; D) 1. CICOCH2CH3, AlCl3 2. FeBrz, Br2 2. FeBr3, Br2 2. FeBr3, Br23. Zn(Hg), HCI 2. Zn(Hg), HCI 3. FeBrz, Br2

Answer 1

Solution и в V о as per given in the question — ун сос Bufg7 37 - Сня сос и (major proclucl ) NXCO hroy ☺ in Friedel eraft reaction (alkylation), Alkylbenzene is formed. The alkyl group present at benzene increase reactivity via inductive effect & types- Conjugation, which increase reaction rate in Friedel craft acylation, the acyl groups present at benzene de arease reactivity due torm Effect, thus further aylation does not take place. LE Suitable seagent for — is som C ; Delcomary, Alch febrz, ar Zucng), HC1. Coon