Question

Hydro- phobic +2 Hydro- philic 200 50 100 150 Amino acid number 4. Based on the hydropathy plot above, if amino acid # 1 is extracellqlar, please draw a diagram of the polypeptide in the context of a phospholipid bilayer. Is the arrow pointing to an intracellular or extracellular loop? Is the C terminus intracellular or extracellular (10 points)? (*Assume the hydrophobic regions form transmembrane a helixes.)

Answer 1

Please look in the Image :

The intra and extracellular region us hydrophillic in nature where as region between plasma membrane is hydrophobic.

Extracellular 20 memb Yane Ha 50 Tntrucellu etroplearn Lar

The arrow is pointing toward extracellular loop.

The C terminus is extracellular.