A 17-year-old was admitted with epigastric and right lower quadrant pain for one day. The physician immediately suspecte...
A 17-year-old was admitted with epigastric and right lower quadrant pain for one day. The physician immediately suspected appendicitis or pancreatitis as the cause of the pain. Laboratory evaluation revealed an elevated WBC.
Chemistry results were as follows: AST 14 U/L (5-35) ALT 18 U/L (7-45) ALP 49 U/L (42-98) Amylase 539 U/L (28-100) Urinary Amylase 52 U/L (40-140) Creatinine 1.0 mg/dL (0.6-1.1) Urinary creatinine 31 mg/dL (500-2000 mg/day) Lipase 36 U/L (<38)
1. State the formula and calculate the amylase/creatinine clearance ratio. Is the value for this patient normal, high or low?
2. Are the laboratory results consistent with acute pancreatitis? If not, what condition explains the elevated amylase?
3. Explain the mechanism for the elevated amylase in this condition?
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