Question

4. Suppose you are investigating an outbreak of an infectious disease in a small area (Region A) of a country. Your team does a random survey of 1,000 people who live in Region A and find that there are 182 cases. a) What measure(s) of disease occurrence can be calculated here? Calculate and interpret the measure(s). Calculate and interpret a 95 %CI for any measure you calculate. 5. Your boss at the Centers for Discase Control has you go back to the same area six months later. Your team does another random survey of 1,000 people (all are different from the subjects in #1 ) and finds 110 cases. In addition, 100 people who were in the first survey and did not have the discase at that time are re-examined and 10 are found to have had the illness during the preceding six months. a) What measure(s) of disease occurrence can you calculate? Calculate and interpret the measure(s) 6. Your bosS wants more information. You're sent back to Region A to enroll 2,000 people in a study. All subjects are free of the disease at the time of enrollment. After three months, 150 of the people have contracted the disease of interest. a) What measure(s) of disease occurrence can be calculated? Calculate the measure(s). Calculate 95 %Cls for any measure you construct. 7. Interested in even more information, your boss sends you back to Region A (where you're getting rather tired of visiting). This time, 1000 disease-free people from Region A (the exposed) are enrolled and 1000 disease-free people from a different area (Region B, the unexposed) are also enrolled in a study. After six months, you check back on your subjects and find that 200 of the 1000 subjects in Region A have contracted the illness., Of these 200, 37 have died. For the 1000 subjects in Region B, 40 have contracted the illness and 7 of these people have died. a) Set up the relevant data in a 2x2 table. Calculate the appropriate measure of association. Interpret b) What is the case fatality in Region A? In Region B? c) What is the survival rate in Region A and B? Is this illness more who get it in A or B (or about the same)? dangerous for individuals 8. Suppose that a particular exposure is suspecting of being a strong risk factor for contracting this disease. You examine 300 people with the disease and find that 170 have the exposure of interest. You also examine 300 people without the disease and find that 90 have the exposure of interest. a) Set these data up in a 2x2 table. Calculate the appropriate measure of association and interpret. Calculate and interpret the 95 %CI for the measure you construct. 9. Below is a graph summarizing the relationship between deep-vein thrombosis (DVT) and estrogen dose contained in oral contraceptives.

Answer 1

As per HomeworkLib policy I can solve the first question, i.e. question number 4.

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