Question

1. Describe two differences and one similarity between base excision repair and nucleotide excision repair.

2. Compare and contrast the genomes of prokaryotes and higher eukaryotes with respect to the following features. a. Presence and number of repeated sequences b. Gene structure c. Approximate gene number

3. Describe three ways in which eukaryotic transcription initiation is different from prokaryotic transcription initiation.

4. Compare and contrast how selection of the translational start site occurs in bacterial and eukaryotic mRNAs.

5.  In both prokaryotes and eukaryotes, groups of genes can be regulated simultaneously (coordinately expressed). However, each group accomplishes this task differently. Explain how coordinate expression differs in prokaryotes compared with eukaryotes.

Answer 1

Similarity - Both Base excision repair(BER) and Nucleotide excision repair(NER), repair chemical damage.

Base excision repair:-

(1) Base excision repairs damage caused by endogenous mutagens.

(2) Damage it repairs is non-distorting to DNA helix.

Nucleotide excision repair:-

(1) Nucleotide excision repairs damage caused by exogenous mutagens.

(2) Damage it repairs is distorting to DNA helix.

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