8. Give the structures of the expected product(s) of the folowing reactions. If more than one product is reasonable...
4. Complete the following reactions, providing the proper stereochemistry where required. If more than one product is possible, indicate the major product. a) Bry CH Но b) 1) ВН THF CH3 2) Н,О, NaOH Hа сн, Pd сн, d) Нer ROOR e) RCO H 1) Hg(OAch, H2O 2) NaBH З/19
4. Complete the following reactions, providing the proper stereochemistry where required. If more than one product is possible, indicate the major product. a) Bry CH Но b) 1) ВН THF CH3 2) Н,О, NaOH Hа сн, Pd сн, d) Нer ROOR e) RCO H 1) Hg(OAch, H2O 2) NaBH З/19
umroeunene Predict the products of the following reactions. When more than one product is expected, predict which will be the major product. OH H,SO (b) H,PO heat 1,38 x) en Nauciet). Y yo hasa, tet z z Noche
Chem 6A Homework #8 (28 pts) Due: 12/2/19 in class Give the organic product(s) of the following reactions Name Write your answers on this sheet. 1) CH3CH Mg CH3CH2CH2CI 2) H,о 1)LIAIH 2) н,б осн, н 1) ether Acetone CH3CH2CH2LI + 2) н,о* Hас Он 1) NaBH 2) н,о' BrMgсHCH,CHз CH2CH3 2) Н,о он Он РСС он PBr он о о но TsCl KCN CH3CH2OH
1. Give the product(s) of the following reactions. If more than one product is expected, label them as major and minor. Show stereochemistry clearly when important. (3 pts, cach reaction) NBS ~ light он HI H. Na SCH acetone Brlow temp 2. What would be the best way to synthesize the following compound from an alkyl halide using a nucleophilic substitution reaction? (4 pts.)
Give the major product(s) (indicating stereochemistry where
appropriate) of each of the following reactions.
он a) 2. 3. H (any strong acid) 1. HBr(1 equiv) MgBr, then 20 2. Mg then H20 OH c) 2. MeMgBr, then H20 3. PBr3, pyridine 4. NaCN 1. HBr (2 equiv) 2. NaNH2 (2 equiv) d) 1. BH3 2. HOOH, NaOH 3. TsCI, pyridine 4. NaSH
PROBLEMS 1. Reagents. Give the structures of the major products (A-G) expected from the following reactions. Assume standard aqueous workup conditions are used for product isolation. a. OH 1. TBSCI imidazole, CH2Cl2 ► DMF, -18°C tot HO OH2. NalO4, CH2Cl2 large excoss A 80% b. олон 1. TSCI. py B "CH, 2. LiEt3BH. THE c. MeOC O H OH 1. TICI (1 cq) py, cat. DMAP - 2. TBSOT 2,6-lutidine, CH2Cl2 C1 79% 3. LIBHA, THE 4. Php. 12 imidazole...