Question

5. Patient: 18 kg child with bacteremia and bacterial meningitis Prescribed Medication: Administer ranitidine (Zantac) 18 mg. IV, every 6 hours Medication Reference 2 to 4 mg/kg/24 hours in equally divided doses every 6 to 8 hours. Do not exceed 50 mg/dose Recommended Dose: Dilution of solution must be no greater than 2.5 mg/ml Too rapid administration has precipitated rare instances of bradycardia, tachycardia, and PVCs. Administer each 50 mg dose over 15 to 20 minutes Dilution: Rate of Administration: Medication Label Calculate the therapeutic range: Is the concentration of the medication acceptable? o is

please show me how to work this out, Thank you

Answer 1

1. Calculate the therapeutic range:.

2-4 mg/ kg/ 24 hours

So

4× 18/24hours

72mg/ 24 hours

This is therapeutic range.

2.yes, concentration is acceptable.

Mixing raniditine with 10ml N.S is adequate.

3. Rate of administration:

Its also correct.

Rational

Total dose per day is 72mg.

Here,

Patient is getting 18 mg ( four times a day, every 6 hourly.

18mg×4= 72mg.

So rate of administration is correct.