Question

al 2019 Assignment 10 75 pts Due at the begin 6.) The gastric pump found in the plasma membrane of gastric m concentration of K of 145 mM and an H concentration 0.15 M. concentration of Kis 10 mM and the contration is at the beginning of November 22 mucosa cell maintains a cytostolic M. In the stomach, thie i nthe (A) (2 pts) What is the pH of the cytosol of pastri pH = -log[A+] Cyt050) = -109 (3x108M of gastric mucosa cells and what is the pll of the stomach dest source Stimach = -log[ 15M] =1.82 (B) (3 pts) What is the change in free energy Stomach at 37 °C?F-96,500 /mol-V, R-8314 is + 70 mV (Cytosol - Stomach ) Skoracimov Cytok --Sorteacha Stomach 000 J/mol-V, R 109 3x10-8M] =117.52 -cytosol pH 15M] -1.82 - Stomach PH the change in free enervarenesting hole of H ome Store cytosor ACERTIN (P + ZAFAY 33621.127 Ah-(8.314 I) (310K) in 6.15] + (+1) 91500 I (70610-3x) +403 83145 J/molok The transmembrane electrical polena ay 33621.427 Mely (C)(3 pts) What is the change in free C 3.10X106 pes) What is the change in free snsrey of transporting I mole of K from the stomach into osol at 37 CPF-96,500 J/mol-V.R 83145 Amol-K. The transmembrane electrical potentia - 70 mV (Stomach - Cytosol). lumM 16=(8.314 IM310F) in Tomm] +(1) (also mi v - 70x10 (D) (3 pts) What is the change in free energy of transporting 1 mole of H' from the cytosol into Stomach and I mole of K from the stomach into Cytosol at 37 °CF-96,500 J/mol V,R-8.3145 J/mol K. The transmembrane electrical potential is - 70 mV (Stomach - Cytosol). G=(8.314 7 1 4 ) (Stok) in )+ (1194500 ot v) (70 x103) (E) (2 pts) Is this transport exergonic or endergonic? (F (3 pts) Under cellular conditions in the gastric mucosa cell, the free energy change for the hydrolysis of ATP is around - 70 kJ/mol. What is the change in free energy of transporting i mole of from the cytosol into Stomach and I mole of K from the stomach into Cytosol at 37 °CE 96,500 J/mol-V, R-8.3145 J/mol K. The transmembrane electrical potential is - 70 mV (Stomach - Cytosol ),when the transport is coupled with ATP hydrolysis? -70KJ/MOL 06 (G) (2 pts) What type of transport is this?

Answer 1

Free energy change can be correlated with the Faraday constant and electrical potential in the following manner.

-

AG= nFe

where 'n' is the number of electron involved in the process

b) Delta G = -nFE

= -1(96500 J mol^-1V^-1) (70 X 10^-3 V)

= -7044 J/mol

Delta G = -7.044 kJ/mol

c) Delta G = -nFE

= -1(96500 J mol^-1V^-1) (-70 X 10^-3 V)

= +7044 J/mol

Delta G = +7.044 kJ/mol

d) Delta G = -nFE

= -1(96500 J mol^-1V^-1) (-70 X 10^-3 V)

= +7044 J/mol

Delta G = +7.044 kJ/mol