Question

10. State 4 major differences between fatty acid synthesis and fatty acid degradation. (16 points) a. b. d. 10, Write an equation for the complete oxidation of palmitate. Using the products from the stoichiometric equation, calculate the ATP yield. (20 pts)

Answer 1

Answer=

Four major differences between fatty acid synthesis and fatty acid degradation are as follows:

a. fatty acid synthesis takes place in cytosol while fatty acid degradation takes place in mitochondrial matrix.

b.Intermediates in fatty acid synthesis are covalently linked to the sulfhydryl groups of an acyl carrier protein (ACP) ,whereas intermediates in fatty acid degradation are covalently attached to the sulfhydryl groups of coenzyme A

c.The enzymes of fatty acid synthesis in higher organisms are joined in a single polypeptide chain called fatty acid synthase.while  fatty acid degradation enzymes do not seem to be associated.

d.The growing fatty acid chain is elongated by the sequential addition of two-carbon units derived from acetyl-CoA.The activated donor of two carbon units in the elongation step is malonyl ACP.the elongation reaction is driven by the release of CO2.

e.The reactant in fatty acid synthesis is NADPH,whereas the oxidants in  fatty acid degradation are NAD+ and FAD.