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5. Complete the following reactions by filling in the missing Reactants, Reagents, or MAJOR Product. If TWO products are equa

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Answer #1

A ) Lactones ( cyclic esters ) are reduced to lactols ( cyclic hemiacetals ) with DIBAL-H at low temperatures.

  DIBAL- H о-н 17 2. Нзот он

B ) The treatment of carboxylic acids with a mixture of bromine and tribromo phosphorus yields the \alpha - Bromo carboxylic acid. ( Hell - Volhard - Zelinsky reaction )

kaH B,PB3 OH OH 2) H2 O OH O -bydroryad)

C ) Nitriles are reduced to primary amines by LiAlH4

  NH2 LiAIH CEN

D )

LOA, Dry THF DIBAL-H H

E )

  eauiv. LDA/THF 1-2 2) Br

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