A ) Lactones ( cyclic esters ) are reduced to lactols ( cyclic hemiacetals ) with DIBAL-H at low temperatures.
B ) The treatment of carboxylic acids with a mixture of bromine and tribromo phosphorus yields the - Bromo carboxylic acid. ( Hell - Volhard - Zelinsky reaction )
C ) Nitriles are reduced to primary amines by LiAlH4
D )
E )
5. Complete the following reactions by filling in the missing Reactants, Reagents, or MAJOR Product. If...
3. Give the major product(s) or provide the correct missing substrate or reagent for each of the following reactions. Pay attention to the regiochemistry and stereochemistry where appropriate. (6 pts) 1) xs. 12, HO- 2) H30* 1) PBr3, Br2 2) CH3OH Eto EtOH, A 1) LDA, THF, -78 °C 1) Eto- 2) Br 3) H307, A Eto Et 1) Eto-, EtOH homlo + Ph Ho 2) H30+
7. (3 pts each) Write the correct reactant, reagents, or major product of the following reactions он TSCI Nal pyridine DMSO HBr EtOK EtOH CH2l2, Zn/Cu Et20 Br2 hv ONa Ph3PBr2 он elimination product Name: Page 6 of
II. Reactions: Predict the major organic product(s) or write the appropriate reagents/starting materials for the following reactions. Indicate stereochemistry and regiochemistry when appropriate. Indicate reactions that are expected to result in a racemic mixture of products DBr 1. Н.О, CHCI он HSO, heat кон 1) вн, THF 3. 2) H202. HO 1) Hg(OAc)2, CH,OH 2) NaBH, OH 5. Br2 SH 6. HIO4 OH THF, H2O "он III. Synthesis: Starting from the alkenyl bromide below, devise a synthesis that produces the...
Provide the missing reagent or major organic product from the following reaction sequence. Take note of the direction of the arrows. Write only the corresponding letters or numbers in the space provided. If the reagent or product is not available then write NONE. Assume aqueous workup is applied at the end of the reaction except for deprotonation reactions. Br 2 PhMgBr х Dess Martin (CH3)2Culi Y REAGENT BANK A. PBrz, Br2 D. NaOEt, EtOH G. CH3OH B. HBr, Br2 E....
Complete the following reactants by writing the missing reactant(s), reagent(s) or major product(s). Include stereochemistry where required . For F (top structure ) - I please ay na ОН OH H2SO4 alcohol carboxylic acid HBr CH2Cl2 POCI: Pyridine НО
*Ignore the structures drawn in pencil. The purple lines indicate that they are incorrect. 23. As 5 points. Complete 10 of the 15 following reactions by providing the missing information: reactants products or reagents and conditions. When predicting products, you must include all products that will most likely form in an appreciable amount. When more than one product is likely, label the major and minor products. (Watch out for rearrangements). Where appropriate, indicate stereochemistry, as well as whether or not...