If this is the product, what were the 2 carbonyl groups you started with to make...
OH 1-Butyne Acetaldehyde Alkyne anions react with the carbonyl groups of aldehydes and ketones to form alkyayl alcohols. The reaction mechanism between 1-butyne and acetaldehyde includes the following steps: 1. Sodium amide deprotonates the terminal alkyne 2. The alkyne anion acts as a nucleophile and adds to the aldehyde carbonyl: 3. Proton transfer from solvent forms the product alcohol. Diagram the mechanism on a separate sheet of paper, and then draw the structure of the product(s) of step 2. ....
see? do you 22. Which faces of the carbonyl groups b a Re, b Si a Si, b Si (A) (B) a Si, b Re (C) a Re, b Re (D) 23. In the reaction, if the pro-S hydrogen is replaced with bromine, what is the product? Br2 CH3 C. PBr3 HH Br II II C Br CH2 (B) (A) HH H H 11 11 CH3 CHS-C (D) (C) OH HO Br H H Br 3W
II. What carbonyl compounds and Grignard reagents would you use to make the alcohols shown below? Show all possibilities. No mechanism necessary. (8 pts) НО. b OH
Which of the following are not electron-withdrawing groups? b oc Od Oe Sufony Nitro Cyano Carbonyl Alkyl What is the major product of the following reaction? HF 0°C Which of the following would not be aromatic (i.e., which would not be unusually stable)? CH; 0 H3C CA
7. Retrosynthetic Analysis a. There are TWO different combinations of the Grignard reagent and carbonyl that can be used to make the product below. Think about TWO ways to make the product, listing the carbonyl and Grignard reagent in the designated boxes ОН Grignard Reagent Carbonyl or 2. Hао* Grignard Reagent Carbonyl b. There are THREE different combinations of the Grignard reagent and carbonyl that can be used to make the product. Please draw the three possible cominations of carbonyl...
7. Retrosynthetic Analysis: a. There are two different combinations of the Grignard reagent and carbonyl that can be used to make the product below. Think about TWO ways to make the product, listing the carbonyl and Grignard reagent in the designated boxes. Carbonyl on Grignard Reagent or 2H40 2. H.O Carbonyl Grignard Reagent b. There are THREE different combinations of the Grignard reagent and carbonyl that can be used to make the product. Please draw the three possible cominations of...
Grignard reagents are used to make C-C new bonds. Their reaction with carbonyl compound leads to alcohols. However, when reacted with carboxylic acids carbonyl compounds are formed. Predict what should be the product of the reaction between 4-nitrobenzoic acid and phenyl magnesium bromide and explain in few chosen words why a carbonyl compound instead of an alcohol.
In the NMR of your product you were able to see a singlet at 10 ppm, what conclusion can you make? The product is 4-methoxybenzalecetophenone, created by an aldol condensation reaction using benzaldehyde and 4-methoxyacetophenone. a. This corresponds to the deuterated solvent b. This corresponds to product c. You broke the NMR, nothing shifts that far downfield d. There is unwanted started material remaining
8. Give the Grignard and Carbonyl compound needed to make each of alcohols. (6 points, 2 each) nd needed to make each of the following you - 9. Circle the compounds that could not be made into a Grignard Reagent. Br 10. Show how you could convert the compound below into a Grignard reagent without having it destroy itself. (4 points)
what alkyl groups make up the following ketone
3) What alkyl groups make up the following ketone? Ph A) Phenyl, pentyl B) Hexyl, phenyl C) Benzyl, hexyl D) Benzyl, heptyl E) None of these choices.