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The [α] of pure quinine, an antimalarial drug, is −165. If a solution contains 67% quinine...

The [α] of pure quinine, an antimalarial drug, is −165. If a solution contains 67% quinine and 33% of its enantiomer (ee = 34%), what is [α] for the solution?

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Answer #1

[alpha] for pure quinine = - 165

Enentiomeric excess (ee)= 34%

[alpha] for solution= ee*[ alpha] of pure solution

=34*(-165)/100= - 56.1degree

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