Which of the following functional groups has a
pKa value of 6.14?
A. carboxylic acid/carboxylate
B. imidazolium/imidazole
C. ammonium/ammonia
Which of the following functional groups has a pKa value of 6.14? A. carboxylic acid/carboxylate B....
What is the major form for each acidic group of histidine when the pH of the solution is 7.00? A. Carboxylic acid; imidazolium; ammonium B. Carboxylate; imidazole; ammonium C. Carboxylate; imidazolium; ammonia D. Carboxylate; imidazolium; ammonium I know its not A or B
If Ca2+Ca2+ is often bound on the surface of a protein by carboxylic acid functional groups. If the pKa of a particular −COOH−COOH group is 4.4, would you predict Ca2+Ca2+ to be most tightly bound at pHpH 7, pHpH 4.4, or pHpH 3?
List the charge of the functional groups at: the pH indicated (right) The pKa is indicated in () Amino (9) Carboxylic Acid (2) Hydroxyl (>14) Sulfhydryl (8)
Provide approximate pKa values for the following functional groups or compounds and provide and example of each: 1) alkane 2) alkene 3) alkyne 4) alcohol 5) phenol 6) water 7) ketone/aldehyde 8) carboxylic acid 9) amine
the two carboxylic acid groups of aspartic acid have different acidities with pKa values of 2.1 and 3.9. Predict which acid group is the more acidic by considering the effect of the -nh3+ group on the stability of the conjugate bases. Explain your reasoning.
Alanine is a diprotic amino acid with a pka = 2.344 for the carboxylic group and a pka = 9.868 for the ammonium group. At pH = 6.32, what is the principal species in solution? a. H2L+ b. c. HL d. H3L2+ e. L2-
Maleic acid contains two carboxylic acid groups, one with a pka of 2.0 and a second with a pKa of 4.0. The fully protonated from of malice acid is shown on below. Briefly describe how you would prepare 0.25L of a 0.1 M buffer at pH = 2.0, assuming that you are starting with the disodium salt of the acid. You should give the moles of sodium malate (MW 178.05 g/mol ) and HCL (36.46 g/mol) that you would need...
the list of functional groups are: aldehyde, alcohol, carboxylic acid and ketone From the list of functional groups, choose the one that corresponds to the description Least oxidized Choose... Most oxidized Choose...
One of the problems with excellent data in vitro is that it is not always guaranteed to be equivalent to data in vivo. Therefore, it is important that what gives in vitro problems are resolved before getting the drug into in vivo studies to give it a better chance. For the following problems, how would you address each of the following for a target in the ER (CFTR)?1. If the drug is a small molecule with a carboxylic acid functional group...
which of the following functional groups or functionalities you can find? -a conjugated pi system -carboxylic acid -ester -hemiacetal -alkyl halide -syraahydrid -acetal -amide HO' ОН МАА АААААА АНАААААААААА