Question

Student signature 1. Somatic cell nuclear transfer is technique that is commonly used to clone mammals. However, research has demonstrated that only a few percent of the resulting embryos complete development and many of those that do complete development die shortly after birth. In contrast, when a nucleus from an undifferentiated embryonic stem cell is transferred into an egg cell, the percentage of embryos that complete development is significantly higher. Propose a possible reason for why successful development of cloned embryos is higher when the nucleus transferred comes from an undifferentiated embryonic stem cell. Provide references for the peer-reviewed articles you use for this discussion (7 points).

Could anyone help me with this question? Please explain it in detail! Thank you so mcuh

Answer 1

ANSWER :

To produce clone mammals the nucleus of undifferentiated embryonic stem cells are preferred over differentiated stem cells nucleus to successful development of clones embryos via somatic cell nuclear transfer technique.

Since, undifferentiated embryonic stem cells are pluripotent which have ability to generate any kind of cell in the body via differentiation in later but already differentiated stem cells cannot do this function hence, if used in clone formation the there would be more chance of fetal death shortly after birth due to non-differentiation of stem cell nucleus to various types of cells such as muscle cells, osteocytes, blood cells, neurons and other.