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SHOW YOUR WORK, PLEASE WRITE LEDGIBLY AND CLEARLY 1. Patch clamp recording of a single ion...
Help with all questions 1. Patch clamp recording of a single ion channel yields the following...
Help with all questions
1. Patch clamp recording of a single ion channel yields the following results Holding Potential Measured Current (mV)(pA) 0.0 -100 -50 +2.0 +3.0 ta +50 +100 A) Draw a graph of the current (on the vertical axis)-voltage relation for this channel. B) What isthe electrical resistance ohms of this channel? keep in mind mv= 103 volts, pA 1012 amperes, and an ohm is a derived unit that is equivalent to a volt/ampere, i.e. a VIA) C)...
1. Patch clamp recording of a single ion channel yields the following results: Holding Potential Measured...
1. Patch clamp recording of a single ion channel yields the following results: Holding Potential Measured Current (mV)10 -100 (pA) -50 0.0 +50 +100 +2.0 +3.0 A) Draw a graph of the current (on the vertical axis)-voltage relation for this channel. B) What is the electrical resistance (in ohms) of this channel? (keep in mind mV- volt/ampere, i.e. a VIA) C) What is the conductance of this channel in siemens (S)? (keep in mind 1 S 1/ohm). D) What would...
please write thorough answers thanks PART 1 Answer ONLY ONE of the following TWO questions of...
please write thorough answers thanks
PART 1 Answer ONLY ONE of the following TWO questions of Part 1 ie a) OR b) a) A typical, healthy nerve cell in the body has intracellular and extracellular Na, K and Cl' concentrations as shown below. Na concentration: Extracellular: = 150 mm K concentration: Extracellular: = 4 mm Ci concentration: Extracellular: = 100 mm Temperature = 37°C (303.3K) R (the Universal Gas constant) = 8.315 VCmol'k F (Faraday's constant) = 96,485 Cmol Intracellular:...
29 Figure Q12-4 shows a recording from a patch-clamp expeniment in which the electrical current passing across a patch of membrane is measured as a function of time The membrane patch was plucked...
29 Figure Q12-4 shows a recording from a patch-clamp expeniment in which the electrical current passing across a patch of membrane is measured as a function of time The membrane patch was plucked from the plasma membrane of a muscle cell by the technique shown in figure 12-24 in the textbook and contains molecules of the acetylcholine receptor, which is a ligand-gated cation channel that is opened by the binding of acetylcholine to the extracellular face of the channel To...
Please show all work 10. Suppose point A is 0.4m from point B. a. What is...
Please show all work
10. Suppose point A is 0.4m from point B. a. What is the conduction time required for an action potential to travel this distance if a single neuron spans this distance and has a conduction velocity is 60m/sec? b. What is the conduction yelocity if the pathway consists of three neurons, two synapses and the synaptic delay is 1 msec? 11. Ohm's Law describes the movement of ions across a membrane: I-G(Vm-E). I is the current...
You are studying neurons in the lab by growing them in culture (in a petri dish outside the body)
You are studying neurons in the lab by growing them in culture (in a petri dish outside the body). You grow them in an incubator at 37 degrees C. With this experimental setup, you can easily change the extracellular ion concentrations by switching the cell culture medium (the fluid that surrounds the cells).Intracellular concentrationMedium 1 (extracellular concentration)Medium 2 (extracellular concentration)K+140 mM4.5 mM50 mMNa+10 mM135 mM100 mMCl-12 mM125 mM120 mMa.If you switch from Medium 1 to Medium 2, will the intracellular...
Cell # 1 forms an excitatory synapse onto cell # 2 , when cell #1 fires a single action potential...
Cell # 1 forms an excitatory synapse onto cell # 2 , when cell #1 fires a single action potential it releases glutamate onto the membrane of cell #2 resulting in a 5 millivolt depolarization, a 5 mV excitatory postsynaptic potential, when cell #1 fires three action potentials in rapid succession this causes a 15 mV depolarization in cell #2 resulting in cell #2 reaching threshold and firing its own action potential. Cell #1 Cell #2 +40 Vm IN Cell...
please explain steps and show work no pictures were provided. table 3.13 is given above. 3.46...
please explain steps and show work
no pictures were provided. table 3.13 is given above.
3.46 The cell membrane is covered with protein complexes called Na-K+ pumps. Each pump moves 3 Nations from the intracellular space to the extracellular milieu for every 2 K ions it moves into the cell. During normal function, the pumps work constantly. Under normal conditions, there is a gradient of Nat and K ions between the cell and the extracellular space; the concentrations of these...
*** I need help with PART F of this problem. Hints are given in other parts...
*** I need help with PART F of
this problem. Hints are given in other parts of the problem and all
information available is given on the worksheet. Please help, thank
you!
The post-synaptic cell at a chemical synapse has the following distribution of ions between the cytosol and the extracellular environment. Consider that the relative permeabilities for Na, K and Cl' are 1, 100 and 50, and that there are no other significant permeabilities, lon Concentration (in mM) Extracellular...
***I need help on PART E of this problem. All of the information is given on...
***I need help on PART E of
this problem. All of the information is given on the worksheet
along with the hints on each part. Thank you!
The post-synaptic cell at a chemical synapse has the following distribution of ions between the cytosol and the extracellular environment. Consider that the relative permeabilities for Na, K and Cl' are 1, 100 and 50, and that there are no other significant permeabilities, lon Concentration (in mM) Extracellular Equilibrium potential mV) Intracellular 146...
Help with all questions
1. Patch clamp recording of a single ion channel yields the following results Holding Potential Measured Current (mV)(pA) 0.0 -100 -50 +2.0 +3.0 ta +50 +100 A) Draw a graph of the current (on the vertical axis)-voltage relation for this channel. B) What isthe electrical resistance ohms of this channel? keep in mind mv= 103 volts, pA 1012 amperes, and an ohm is a derived unit that is equivalent to a volt/ampere, i.e. a VIA) C)...
1. Patch clamp recording of a single ion channel yields the following results: Holding Potential Measured Current (mV)10 -100 (pA) -50 0.0 +50 +100 +2.0 +3.0 A) Draw a graph of the current (on the vertical axis)-voltage relation for this channel. B) What is the electrical resistance (in ohms) of this channel? (keep in mind mV- volt/ampere, i.e. a VIA) C) What is the conductance of this channel in siemens (S)? (keep in mind 1 S 1/ohm). D) What would...
please write thorough answers thanks
PART 1 Answer ONLY ONE of the following TWO questions of Part 1 ie a) OR b) a) A typical, healthy nerve cell in the body has intracellular and extracellular Na, K and Cl' concentrations as shown below. Na concentration: Extracellular: = 150 mm K concentration: Extracellular: = 4 mm Ci concentration: Extracellular: = 100 mm Temperature = 37°C (303.3K) R (the Universal Gas constant) = 8.315 VCmol'k F (Faraday's constant) = 96,485 Cmol Intracellular:...
29 Figure Q12-4 shows a recording from a patch-clamp expeniment in which the electrical current passing across a patch of membrane is measured as a function of time The membrane patch was plucked from the plasma membrane of a muscle cell by the technique shown in figure 12-24 in the textbook and contains molecules of the acetylcholine receptor, which is a ligand-gated cation channel that is opened by the binding of acetylcholine to the extracellular face of the channel To...
Please show all work
10. Suppose point A is 0.4m from point B. a. What is the conduction time required for an action potential to travel this distance if a single neuron spans this distance and has a conduction velocity is 60m/sec? b. What is the conduction yelocity if the pathway consists of three neurons, two synapses and the synaptic delay is 1 msec? 11. Ohm's Law describes the movement of ions across a membrane: I-G(Vm-E). I is the current...
Cell # 1 forms an excitatory synapse onto cell # 2 , when cell #1 fires a single action potential it releases glutamate onto the membrane of cell #2 resulting in a 5 millivolt depolarization, a 5 mV excitatory postsynaptic potential, when cell #1 fires three action potentials in rapid succession this causes a 15 mV depolarization in cell #2 resulting in cell #2 reaching threshold and firing its own action potential. Cell #1 Cell #2 +40 Vm IN Cell...
please explain steps and show work
no pictures were provided. table 3.13 is given above.
3.46 The cell membrane is covered with protein complexes called Na-K+ pumps. Each pump moves 3 Nations from the intracellular space to the extracellular milieu for every 2 K ions it moves into the cell. During normal function, the pumps work constantly. Under normal conditions, there is a gradient of Nat and K ions between the cell and the extracellular space; the concentrations of these...
*** I need help with PART F of
this problem. Hints are given in other parts of the problem and all
information available is given on the worksheet. Please help, thank
you!
The post-synaptic cell at a chemical synapse has the following distribution of ions between the cytosol and the extracellular environment. Consider that the relative permeabilities for Na, K and Cl' are 1, 100 and 50, and that there are no other significant permeabilities, lon Concentration (in mM) Extracellular...
***I need help on PART E of
this problem. All of the information is given on the worksheet
along with the hints on each part. Thank you!
The post-synaptic cell at a chemical synapse has the following distribution of ions between the cytosol and the extracellular environment. Consider that the relative permeabilities for Na, K and Cl' are 1, 100 and 50, and that there are no other significant permeabilities, lon Concentration (in mM) Extracellular Equilibrium potential mV) Intracellular 146...
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