A biochemist needs 750 mL of an acetic acid–sodium acetate buffer with pH 4.50. Solid sodium acetate (CH3COONa) and glacial acetic acid (CH3COOH) are available. Glacial acetic acid is 99% CH3COOH by mass and has a density of 1.05 g/mL. If the buffer is to be 0.15 M in CH3COOH, how many grams of CH3COONa and how many milliliters of glacial acetic acid must be used?
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