Suppose you want to do a physiological experiment that calls for a pH 6.50 buffer. You find that the organism with which you are working is not sensitive to the weak acid H2A (Ka1 = 2 × 10-2; Ka2 = 5.0 × 10-7) or its sodium salts. You have available a 1.0 M solution of this acid and a 1.0 M solution of NaOH. How much of the NaOH solution should be added to 1.0 L of the acid to give a buffer at pH 6.50? (Ignore any volume change.)
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