The cancer drug melphalan is an alkylating agent of the mustard gas family. It acts in two ways: by causing alkylation of guanine bases and by cross linking DNA strands together. Describe two ways in which melphalan might kill cancer cells. What are two ways in which cancer cells could repair the DNA-damaging effects of melphalan?
¦ HINT: This problem asks you to consider the effect of the alkylation of guanine on base pairing during DNA replication. The key to its solution is to consider the effects of mutations on cellular processes that allow cells to grow and divide. In Section 15.5, you will learn about the ways in which cells repair the types of mutations introduced by alkylating agents.
We need at least 10 more requests to produce the solution.
0 / 10 have requested this problem solution
The more requests, the faster the answer.