If one spontaneous mutation occurs within a human egg cell genome, and this mutation changes an A to a T, what is the most likely effect of this mutation on the phenotype of an offspring that develops from this mutated egg?
•HINT: This problem asks you to predict the effects of a single base-pair mutation on phenotype. The key to its solution involves an understanding of the organization of the human genome as well as the effects of mutations on coding and noncoding regions of genes, and the effects of mutations on development.
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