A number of human-mouse somatic cell hybrid clones were examined for the expression of specific human genes and the presence of human chromosomes. The results are summarized in the following table. Assign each gene to the chromosome on which it is located.
Hybrid Cell Clone | ||||||
| A | B | C | D | E | F |
Genes expressed | ||||||
ENO1 (enolase-1) | – | + | – | + | + | – |
MDH1 (malate dehydrogenase-1) | + | + | – | + | – | + |
PEPS (peptidase S) | + | – | + | – | – | – |
PGM1 (phosphoglucomutase-1) | – | + | – | + | + | – |
Chromosomes (present or absent) | ||||||
1 | – | + | – | + | + | – |
2 | + | + | – | + | – | + |
3 | + | + | – | – | + | – |
4 | + | – | + | – | – | – |
5 | – | + | + | + | + | + |
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