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As parents of an autistic child, entering a research study seemed to be a way of not onl...

As parents of an autistic child, entering a research study seemed to be a way of not only educating themselves about their son's condition, but also of furthering research into this complex, behaviorally defined disorder. Researchers told the couple that there is a strong genetic influence for autism since the concordance rate in identical twins is about 75 percent and only about 5 percent in fraternal twins. In addition, researchers have identified interactions among at least ten candidate genes distributed among chromosomes 3,7, 15, and 17. Generally unaware of the principles of basic genetics, the couple asked a number of interesting questions. How would you respond to them?

What is a "candidate" gene?

As parents of an autistic child, entering a research study seemed to be a way of not only educating themselves about their son's condition, but also of furthering research into this complex, behaviorally defined disorder. Researchers told the couple that there is a strong genetic influence for autism since the concordance rate in identical twins is about 75 percent and only about 5 percent in fraternal twins. In addition, researchers have identified interactions among at least ten candidate genes distributed among chromosomes 3,7, 15, and 17. Generally unaware of the principles of basic genetics, the couple asked a number of interesting questions. How would you respond to them?

What is a "candidate" gene?

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