In light of indications that there are at least 19,000 pseudogenes in the human genome and perhaps as few as 21,000 protein-coding genes, some researchers suggest that as assays become more refined, the number of pseudogenes may outnumber protein-coding genes (Gerstein and Zheng, 2006).
(a) Why would it take more time to locate pseudogenes than protein-coding genes?
(b) Most pseudogenes are damaged remains of previously functional genes and are considered to be nonfunctional .However, it has been suggested that some pseudogenes do function. In light of the various ways in which DNA is organized in chromosomes, how might pseudogenes function?
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