More information from the research effort in Problem 26 produced data regarding the pattern of the length of such repeats within genes. Each value in the following table represents the number of times a microsatellite of a particular sequence length, one to six bases long, is found within genes. For instance, in primates, a dinucleotide sequence (GC, for example) is found 10 times, while a trinucleotide is found 1126 times. In fungi, a repeat motif composed of 6 nucleotides (GACACC, for example) is found 219 times, whereas a tetra-nucleotide repeat (GACA, for example) is found only 2 times. Analyze and interpret these data by indicating what general pattern is apparent for the distribution of various microsatellite lengths within genes. Of what significance might this general pattern be?
Distribution of Microsatellites by Unit Length within Genes
Taxonomic Group |
| Length of Repeated Motif (bp) | ||||
1 | 2 | 3 | 4 | 5 | 6 | |
Primates | 49 | 10 | 1126 | 29 | 57 | 244 |
Rodents | 62 | 70 | 1557 | 63 | 116 | 620 |
Arthropods | 12 | 34 | 1566 | 0 | 21 | 591 |
Yeasts | 36 | 19 | 706 | 7 | 52 | 330 |
Other fungi | 9 | 4 | 381 | 2 | 35 | 219 |
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