Problem

To carry out metabolism, oxygen is taken up by hemoglobin (Hb) to form oxyhemoglobin (HbO2...

To carry out metabolism, oxygen is taken up by hemoglobin (Hb) to form oxyhemoglobin (HbO2) according to the simplified equation

where the second-order rate constant is 2.1 × 106/M • s at 37°C. For an average adult, the concentrations of Hb and O2 in the blood at the lungs are 8.0 × 10−6 M and 1.5 × 10−6 M. respectively, (a) Calculate the rate of formation of HbO2. (b) Calculate the rate of consumption of O2. (c) The rate of formation of HbO2 increases to 1.4 × 10−4 M/s during exercise to meet the demand of the increased metabolism rate. Assuming the Hb concentration to remain the same, what must the oxygen concentration be to sustain this rate of HbO2 formation?

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