One method of synthesizing the aspirin substitute acetaminophen involves a three-step procedure as outlined in Figure. First, p-nitrophenol is catalytically hydrogenated in the presence of aqueous hydrochloric acid to the acid chloride salt of p-aminophenol with an 86.9% degree of completion. Next the salt is neutralized to obtain p-aminophenol with a 0.95 fractional conversion. Finally, the p-aminophenol is acetylated by reacting with acetic anhydride, resulting in a yield of 3 kg mol of acetaminophen per 4 kg mol. What is the overall conversion fraction of p-nitrophenol to acetaminophen?
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