Protease inhibitor inhibits the progression of the HIV (human immunodeficiency virus) by blocking the protease enzymes, thereby controlling the production of the HIV proteins. Some, such types of drugs are atazanavir, indinavir and ritonavir.
Coagulases react from the blood prothrombin and in the formation of a complex known as staphylothrombin. It helps the protease enzyme in the conversion of fibrinogen to fibrin, which is a plasma protein and is produced by the liver.
HIV protease acts as a hybrid of protease inhibitor. The HIV is a subgroup of retrovirus and causes infection of HIV as well as after some time leads to AIDS (acquired immunodeficiency syndrome). A situation affects humans as well as results in progression of failure of the human immune system.
HIV protease deals with the long strands of the RNA (ribonucleic acid) of the virus. The RNA is cleaved in the presence of proteases. These drugs act via cleaving of protein precursors that are important for the assembly of infectious viral particles.