Problem

Solutions For An Introduction to Medicinal Chemistry Chapter 20 Problem 5Q

Step-by-Step Solution

Solution 1

Tenofovir disoproxil is also known as Viread (trade name). It is a medication that is used for treating hepatitis B and HIV (human immunodeficiency virus) /AIDS (acquired immunodeficiency syndrome) also. It is recommended to use with other antiretrovirals. Tenofovir disoproxil is an NtRTI (nucleotide analog reverse-transcriptase inhibitor).

It lacks hydroxyl group on itscarbon and thus, prevents elongation of DNA (deoxyribonucleic acid) chain. It leads to termination of transcription and hence, viral replication.

Adefovir is a medication given to treat infections like hepatitis B. Its trade name is Preveon as well as Hepsera. It is administered orally and is administered as a pivoxil adefovir dipivoxil. It works via blocking the enzyme reverse transcriptase activity.

Hepatitis is a chronic or acute inflammation of the liver, which is caused by a hepatotoxic drug or a viral infection. Hepatitis, when caused by an infection is contagious and can be transmitted by contact with blood or sexual intercourse.

Add your Solution
Textbook Solutions and Answers Search
Solutions For Problems in Chapter 20