Chemical development is the large scale production of the market approved drug. The drug synthesized in the laboratory, is synthesized in a small amount. It is not sufficient to cater to the public demand. Also, the synthetic route used to synthesize can also vary. While synthesizing the drug in the laboratory many expensive chemicals are used, as they are required in small amount.
Potentially hazardous chemicals are also used owing to their extremely low concentration required. Market demand for the higher amount is required, which in turn requires more use of the expensive and hazardous chemicals. Therefore, when a drug is approved for market, it can undergo a complete change of synthetic route.
The companies producing the drug will rely on cheaper, less dangerous, high yielding procedure to make the drug. This will ensure that the final product is high yielding. The specifications required for the final product also impacts the materials used in the process.
Toxicity levels, melting points, pH (potential of hydrogen), and purity levels all must be checked for different compounds used. This predetermined optimization, help in securing the developmental stages for all future batches to be made.