Hence the option b is not correct.
During a family studies if the disorder or the disease is more commonly found in the Proband family then that disorder is called the familial or the aggregate in the families.
Hence the option c is not correct.
Clinical samples are the one that are seeking services for a specific problem.
Hence the option d is not correct.
Analogue samples are the people who have the interest of volunteering and resemble treatment seeking individuals but are not seeking clinical services.
Hence the correct option is.