Problem

(a) If we write the Michaelis-Menten equation asit should be possible to integrate it and...

(a) If we write the Michaelis-Menten equation as

it should be possible to integrate it and obtain an expression for substrate concentration as a function of time. Do so, calling [S]0 the initial substrate concentration at t = 0.


 (b) Show from the result in (a) that under conditions where [S]0 >> KM,the decrease in substrate concentration with time is approximately linear. Interpret this result.

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Solutions For Problems in Chapter 11