Question

Identify the best reagents and reaction intermediate by dragging the appropriate label to its position in the following reaction scheme.

Map sapling learning ldentiy the best reagents and reaction intermediate by dragging the appropriate label to its position in the following reaction scheme 2 equiv. NaOH 1 equiv. NaOH 2 equiv. NaOCH3 1 equiv. NaOCH3 2 equiv. CH3Br 1 equiv. CH3CH2Br 1 equiv. CH3COCI 1 equiv. CH3MgBr 2. H2O 2 equiv. LDA 1 equiv. LDA 1 equiv. CH3Br Previous ⓧ Give Up & View Solution O Check Answer Next Exit Hint

Answer 1

In first step, more acidic proton is picked by LDA and next hydrogen taken by another mole of LDA. 2- 1,5-diide obtained as a product In second step, terminal negative charge will be more nucleophilic because it is hackened by one CO group but the inner negative hakened by 2 CO groups. SO t is upon reaction with CH3Br gives 1,3-dioxo-1- phenylpentan-2-ide as product. Which is upon reaction with water and LiBr means hydrolysis in presence of lithium bromide gives 1-phenylpentane-1,3-dione as final product The reactions with reagents and obtained products are as follows: 2 equiv LDA 2-benzoyl-3-oxopentane-1,5-diide 1 Equiv CHBr H2O LiBr 1,3-dioxo-1-phenylpentan-2-ide 1-phenylpentane-1,3-dionoe

Answer 2