Questions 1. Complete the following scheme: 8pts он OH OCH3 1. NaOH 2. Name: Name Name 2. Salicylic acid reacting with acetic anhydride and phosphoric acid is which type of the following reaction? (3PTS) a) Diels Alder b) Saponification c) Acetylation
Write a balanced chemical equation using condensed structural formulas for the saponification (base hydrolysis) of methyl propionate. Express your answers as a chemical expression. CH3CH2C(O)OCH3+NaOH→ Write a balanced chemical equation using condensed structural formulas for the saponification (base hydrolysis) of phenyl acetate. Express your answers as a chemical expression. CH3C(O)OC6H5+2NaOH→
Part A Write a balanced chemical equation using condensed structural formulae for the saponification (base hydrolysis) of methylpropionate Express your answers as a chemical expression. AED ROO? CH3CH2C(O)OCH3 + NaOH - Submit Request Answer Part B Write a balanced chemical equation using condensed structural formulae for the saponification (base hydrolysis) of phenyl acetate. Express your answers as a chemical expression. 1- ALP RO? CH-C(O)OCH + 2NaOH → Submit Request Answer Provide Feedback
4. Methanol and sodium sulfate are byproducts of the saponification. During which step(s) of the synthesis are these compounds separated from the final product? 5. What is the white solid that forms when methyl salicylate is added to the aqueous solution sodium hydroxide? о-осн OCH3 ΟΘ -OCH OH он ONa Na 2. H3O COOCH, NaOH OOCH, NaOH 3 OONa OOH Methyl Salicylate Water insoluble salt Water soluble salt Salicylic Acid
4. Predict the major product of the following reactions. OCH3 excess NaOH excess Br2 a) 1.excess NaOH TBSO excess Br2 2. H30+, dilute, cold 3. SOCl2, py 4. H2N -OCH3 Н3СО Г OY 1. Br2, OH 2. NaSCH2CH3 LIN = LDA, THF, -78°C 1. le 2. To 3. 03 4. H2O2, NaOH, H20 OH, DCC
Mechanism #2. The hydrolysis of esters using base (typically NaOH) is termed "saponification", and is often used to make soaps. Propose a mechanism for the saponification reaction shown below. Remember, hydroxide is a strong nucleophile. OH H20 HO
Mechanism #2. The hydrolysis of esters using base (typically NaOH) is termed "saponification", and is often used to make soaps. Propose a mechanism for the saponification reaction shown below. Remember, hydroxide is a strong nucleophile. & hand "OH H20 HO
Mechanism #2. The hydrolysis of esters using base (typically NaOH) is termed "saponification", and is often used to make soaps. Propose a mechanism for the saponification reaction shown below. Remember, hydroxide is a strong nucleophile. "OH H2O
Which of the following is a hydrate? 0 OCH3 OH OCH3 OOH OH
Fill in the reagent/product/reactant:
OCH3 1) K* -OCH3, HOCH3 2) H30*, A 1) NH,OH, H+ (cat.) 2) H2SO4 O NX OH SOCI 1) LiAlH4 2) H2O NaN3, A NaOH, Bra HO, A