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what is the difference between FDA approved stimulant drugs and designer drugs?

what is the difference between FDA approved stimulant drugs and designer drugs?
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STIMULANT DRUGS; they are psychotic drugs that induce temporary improvements in either mental or physical functions or both. stimulant drugs speed up the person' central nervous system. stimulants make person high

they are prescribed to treat only a few health condition like nacrolepsy , depression---in those who not responded to the other treatrments

eg;cocaine, amphetamine,

DESIGNER DRUGS; the drug produced by minor modification in chemical structure of an existing drug resulting in new substance with similar pharmcological activity, especially one created to achieve same effect as of controlled or illegal drug

eg; spice/k2, bath salts

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