Which of the following metabolic reactions are possible for procainamide, shown below?
−NHCOCH3−NHCOCH3−NHCOCH3
−OCH3−OCH3−OCH3
−CN−CN−CN
−NO2−NO2−NO2
−CH3−CH3−CH3
Which of the following metabolic reactions are possible for procainamide, shown below? −NHCOCH3−NHCOCH3−NHCOCH3 −OCH3−OCH3−OCH3 −CN−CN−CN −NO2−NO2−NO2...
Which of the following metabolic reactions are possible for procainamide, shown below? O-dealkylation Hydrolysis Acetylation N-dealkylation ZI H2N
12) Identify the product for the following reaction? 2 Pts осн, CN Bry/FeBry NO2 осн. OCH3 .CN OCH CN осн, CN CN Br B) A) D) Br Br Br NOZ NOZ NOZ NO2 13) Propose an efficient synthesis for the following transformations? (Multistep Synthesis) 8 Pt NO2 A) ♡ NH2 B)
Which of the following shown below represent a pair of enantiomers? CN (a) Br HAC-C-CN (b) CO2H HC-Br HC-CH? Br HC-CN CO2H (c) (d) CO2H CH3 он H -OH HC-CH2CH3 CH3CH H3C CH3 -CO2H H H2N H3C CH H2N 2 o
Which of the following undergoes the most rapid electrophilic aromatic substitution with Brz/AlBr3 CH3 OCH3 OCH3 OCH3 Br a) b) c) d) NO2 OCH3 OCH3 SO3H LO) What is the major product of this reaction: H2CO Brą, light Product Br Br mootorror H3CO. H3CO. d)
3. Consider the reactions below. Which of the reactions below has the largest Keq as shown? (3 points). O -K+ H-N + Li-N Li-N + H-N C. d. Na+O O + HOCH3 + Na -OCH3 Na+-OH + H20 OCH3 OCH3 3. Consider the reactions below. Which of the reactions below has the largest Keq as shown? (3 points). O -K+ H-N + Li-N Li-N + H-N C. d. Na+O O + HOCH3 + Na -OCH3 Na+-OH + H20 OCH3 OCH3
Substituents on an aromatic ring can have several effects on electrophilic aromatic substitution reactions. Substituents can activate or deactivate the ring to substitution, donate or withdraw electrons inductively, donate or withdraw electrons through resonance, and direct substitution either to the ortho/para or to the meta positions. From the following lists, select the substituents that have the indicated property. The substituents are written as -XY, where X is the atom directly bound to the aromatic ring. Activation of the ring towards...
7 (2 pts). Which of the following reactions will proceed well to give the indicated compounds as the major products? Check all that apply. CI (0) CI CI 1. HNO3, H2SO4 2. HN(CH3)2 NO2 CI 'N (ii) 1. HNO3, H2SO4 2. HN(CH3)2 NO2 CI CI CI 'N OCH3 OCH 1. HNO3, H2SO4 2. HN(CH3)2 ON CI N1 (iv) OCH3 1. NaN(CH3)2, HN(CH3)2 OCH3 2. Br2 Br HC arr HC CI (v) H2C AICIS H2C CH3 CH (vi) - HAN 1)...
Which of the following sets of substituents are all ortho/para directing in electrophilic aromatic substitution reactions? O CN, NO2, COCH3 O CI, OH, CH3 OBr, OH, COCH3 OCI, CH3. CN
Which of the following shown below represent a pair of enantiomers? Which of the following shown below represent a pair of enantiomers? (a) Br CN CC-CN HC-CH3 (b) ÇO2H Br HC-Br HC-CN CO2H Br CN Ich CH3 OH OH (d) CH3 CO2H H-C-OH HC-CH2CH3 CH2CH2 H3C 1. H7C-CO2H HAN H3C 77-H HN. O ཅི O ཆེ O O བྱི
52. Arrange the relative pKa's of the following compounds:( P (2 pts) соон соон COOH pKa's: 53. Arrange th compounds: (2 pts) e relative reaction rates for the electrophilic aromatic substitution of the following CH3 OCHa NO2 Reaction rates: 54. Arrange the relative base strength of the following compounds: (2 pts) NHCOCH3 NH2 NH2 NH2 NH. OCH3 OCH3 Basicity 55. What is the splitting pattern for the labeled hydrogens in the following compounds? (5 pt CH CH 56. Provide one...