Which of the following metabolic reactions are possible for procainamide, shown below?
O-dealkylation
Hydrolysis
Acetylation
N-dealkylation
Correct options:
O-dealkylation
Hydrolysis
Acetylation
Explanation:
Procainamide has an amide bond (N(H)-CO). Hence, hydrolysis of amide is a possible metabolic reaction.
Procainamide has an amine (NH2) functional group. Hence, acetylation of amine is a possible metabolic reaction.
Procainamide has an tertiary amine (NR3) functional group (R = alkyl). Hence, N-dealkylation of amine is a possible metabolic reaction.
There is no O-R group in the structure of procainamide . Hence, O-dealkylation is not possible.
Which of the following metabolic reactions are possible for procainamide, shown below? O-dealkylation Hydrolysis Acetylation N-dealkylation...
Which of the following metabolic reactions are possible for procainamide, shown below? −NHCOCH3−NHCOCH3−NHCOCH3 −OCH3−OCH3−OCH3 −CN−CN−CN −NO2−NO2−NO2 −CH3−CH3−CH3
Which of the following is not a Phase I reaction? a. Oxidation b. Hydrolysis c. Epoxidation d. N-dealkylation e. Acetylation
3. Consider the reactions below. Which of the reactions below has the largest Keq as shown? (3 points). O -K+ H-N + Li-N Li-N + H-N C. d. Na+O O + HOCH3 + Na -OCH3 Na+-OH + H20 OCH3 OCH3
3. Consider the reactions below. Which of the reactions below has the largest Keq as shown? (3 points). O -K+ H-N + Li-N Li-N + H-N C. d. Na+O O + HOCH3 + Na -OCH3 Na+-OH + H20 OCH3 OCH3
The
following questions refers to the acetylation reaction of ferrocene
shown below.
1a) What is the mechanism of the acetylation reaction of
ferrocene?
1b) Compare the behaviour of the cyclopentadienyl group in
ferrocene with that of benzene.
1c) How could the yield of diacetylated product be
increased?
COCH, COCH (CH,CO), H2PO4/heat H COC
7) Why do hydrolysis reactions occur more readily in solution than dehydration reactions? A) Hydrolysis reactions increase G, or Gibbs free energy of the system, B) Hydrolysis reactions are endergonic and increase entropy of the system. C) Hydrolysis reactions are exergonic and decrease entropy of the system. D) Hydrolysis reactions are exergonic and increase entropy of the system. 8) How do cells use the ATP cycle illustrated in the figure? AAA W A) Cells use the cycle to recycle ADP...
Select the correct metabolic phase l or phase Il reactions on the structure below. Sellos NCH, PAA [Choose] [Choose ] No reaction O-Demethlylation Glucuronide or Sulfate conjugation Glutathione conjugation Epoxide N-Demethyla on [Choose ]
Which of the following histone modifications generally PREVENTS transcription from occurring? Methylation o acetylation Demethylation Phosphorylation
Question 44 1.334 poir Which of the following metabolic pathways has some reactions that take place in the cytosol while other reactions take place in the mitochondria? O Aurea cycle OB. fatty acid oxidation C.glycolysis D. pentose phosphate pathway E. citric acid cycle
1. Give the IUPAC names of the molecules shown below Ish a. b. H2N ÇH30 d. CH3-NH-C –CH2-CHCH3 CH3-N—C—CH2-CH3 CH3 to Que ZI
9. What is the major product of the following reactions? Br, CH3NH2 N? Br HO O H2N (CH2)4NH OH HO HO H2O OH OH acid OH OH OH OH 1. NH3, trace acid 2. CN, HCI 3. HCI, H20, A