Question

are there any synthetic transformations produced in this lab

Step 1. Preparation and Recrystallization of a Diastereomeric Salt - Synthesis of (R,R)-1,2-Diammoniumcyclohexane mono-(+)-tartrate: In a 150 ml beaker, L-(+)-Tartaric acid (7.5 g, 0.05 mol) is dissolved in 25 mL of distilled water. The solution is stirred as 11.4 g (12.2 mL, 0.10 mol) of 1,2-diaminocyclohexane is added carefully in one portion. (The addition of the diamine is exothermic.) A slurry is formed initially but complete dissolution is observed once addition is complete. After a few minutes, 5.0 mL of glacial acetic acid is added in one portion. Product begins to fall out of solution shortly after the addition, and it continues to precipitate while the reaction mixture is cooled to 5 °C in an ice/water bath. After sitting for at least 30 minutes in an ice bath at 5 °C, the product is isolated by filtration. The filter cake is washed with 5.0 mL of cold (5 °C) water followed by 4 x 5 mL portions of room temperature methanol. a) While you wait for the solid to precipitate, your instructor will demonstrate how to use the polarimeter by measuring the optical rotation of racemic 1,2-diamino cyclohexane and of (1R 2R)-(--)-1,2-Diaminocyclohexane. Record the results in your notebook and discuss it in your post-lab report. Step 2. Preparation of Jacobsen's Ligand: Formation of a Diimine (R,R)-N,N-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine. A 100 ml, round bottomed flask equipped with a magnetic stir bar is charged with 6.0 mL of water, 1.11 g of (R,R)-1,2-diaminocyclohexane mono-(+)-tartrate salt, and 1.16 grams of potassium carbonate. The mixture is stirred until dissolution is achieved, then A 9

Answer 1

YES, there is synthetic transformation produced in the lab in 2 steps.

1st step is preparation of tartarate salt of 1,2-diamino cyclohexane. Glacial acetic acid used as weak acid catalyst where water soluble tartaric acid reacts with starting material 1,2-diamino cyclohexane to produce its tartarate salt.

2nd step involve reaction of produced tartarate salt with 2,3-Di-tert-butylsalicylaldehyde in ethanol solvent in presence of K2CO3 as catalyst.

Final synthesized product is yellow in color but where desired product obtained or not it can confirm the spectral analysis.