Draw the complete TCA cycle (Krebs or Citric acid cycle). Show the entry of acetyl- COA...
Krebs cycle fill in the blank... In reaction 1 of the Krebs cycle, acetyl-CoA formed in the pyruvate dehydrogenase reaction condenses with the four-carbon compound to form with the elimination of coenzyme A. Since the product has three carboxyl groups, this pathway is referred to as the cycle. In reaction 2 of the Krebs cycle, this product then undergoes to form The enzyme is called aconitase because the compound cis-aconitate is a(n) of the reaction. Reaction 3 eliminates CO_2 to...
Acetyl-CoA labeled with C, as shown, can enter the citric acid cycle. Assuming all the acetyl-CoA enters the cycle... 1. What fraction of the label will be present in oxaloacetate at the end of one turn of the cycle? 14 2. Which carbons in the oxaloacetate formed by one turn of the cycle would contain the radioactive label? C4 C3 C2 Ci .What fraction of the original radiolabel present in the acetyl-CoA will be present in oxaloacetate at the end...
3. Draw one turn of the citric acid cycle starting from a radio-labeled (*) acetyl-CoA shown below. Trace the fate of radio-labeled carbons and fully label each structure of intermediates through the citric acid cycle. Include the names of enzymes involved (in the table below), number each step, and indicate the names of each consumed or produced product. (Hint: There are symmetrical molecules present) (12 marks) CoA Нас 5. 2. 6 7. 3. 4. 8
acetyl-CoA COA The reactions of the citric acid cycle are shown in the image. As labeled in the diagram, reactions 1, 3, and 4 are regulation points in the citric acid cycle. oxaloacetate citrate synthase citrate NADH +Hi 7 malate dehydrogenase NAD malate aconitase 2 Which molecule inhibits reaction 1? isocitrate 7 fumarase NAD isocitrate dehydrogenase 3 NADH + H+ O citrate O NAD acetyl-CoA + CO2 fumarate C-ketoglutarate FADH succinate O dehydrogenase FAD O-ketoglutarate a dehydrogenase NAD + COA...
In unit 2 we learned that the TCA cycle (the citric acid cycle) is a sequence of reactions in mitochondria that oxidizes the acetyl moiety of acetyl-CoA to CO2 and reduces coenzymes that are reoxidized through the electron transport chain. What is is another name for this cycle? Also, name at least three enzymes that are involved in the cycle and briefly explain how they work in the cycle.
8. The citric acid cycle requires acetyl-CoA to begin. Describe how acetyl-CoA is produced for the citric acid cycle.
When acetyl-CoA is fed into the TCA cycle, it eventually forms carbon dioxide. The energy released from this oxidation is conserved in the form of (select all that apply): FADH2 Water GTP Protons NADH
5. In the Citric Acid Cycle, a flavin coenzyme is required for a. Condensation of acetyl-CoA and Oxaloacetate. b. Oxidation of Succinate c. Oxidation of Isocitrate. d. Oxidation of Malate. e. Hydration of Fumarate.
What is the chemical reaction that involves oxaloacetate and acetyl-coa in the tca cycle? a. hydration b. oxidation c. reduction d. hydrolysis e. none of the above
not sure about reaction 3 and 4 acetyl-CoA COA The reactions of the citric acid cycle are shown in the figure Reactions 1, 3, and 4 are regulation points in the citric acid cycle. 1 citrate oxaloacetate 1 synthase citrate NADH + NAD malate dehydrogenase aconitase 2 malate Which of the molecules inhibits reaction 1? Isocitrate HO 17 fumarase NAD socitrate 3 dehydrogenase S D NADP ADP ОАТР O citrate synthase fumarate FADHI succinate co-ketoglutarate dehydrogenase ci-ketoglutarate NAD dehydrogenase +...