1st of All its not mentioned that how much amount of starting materials you are taking. so by myself im calculating for 1 gram. Toluene is sovent here...So you can use it excess.
fill in the blanks please! Pre-Lab for Lidocaine Analog Synthesis - Step 2 Complete the reaction...
Pre-Lab for Lidocaine Analog Synthesis Step 1 1) Complete the reaction table below with the expected quantities used and obtained in this reaction NH2 HN 1) ACOH 2) Na Chloroacetyl chloride 2,6- Sodium a-chloro-2,6- Acetic acid dimethylace tanilide dimethylaniline acetate 0.4 M (aq) FW g/mol g/mol g/mol g/mL g/mL Amount g (Theory) mL mL mL mL (Theory) mmol Equivs 1.0 1.1 2) Draw the mechan is m of this amide formation (you can look up nucleophilic acyl substitution reactio ns...
Complete the reaction table above, including the quantities you used in the reaction, prior to the addition of extra diethylamine 0 0 HN H-N Toluene + 2 HN CI Reflux N(2,6-dimethylphenyl)-2 α-chloro-2.6- dimethylacetanlidepiperidine Toluene FW g/mol g/mL mL g/mol g/mol g (Theory) Amount mmol Equivs. mL mg (Theory) 1.0 3.0 Why do you need an excess of piperidine? (4 pts) What is left in the toluene layer that is discarded after extraction with 3M aqueous HC1? (4 pts) Complete the...
1) Complete the table below in your notebooks and as a pre-lab. Look up the density of acetyl chloride and m.p. of biphenyl on the web (10 pts). CH Cb reflux AICI: C4H20 Biphenyl C12H10 Acetyl Chloride CH3CIO Methylene chloride CH2Cl2 MW (g/mol) 154.2 78.5 133.3 196.2 mg 0.1 mL mg 6 mL Qty. measured Amount (mmol) Stoich. Equivs. mg (theory) (theory) 1.5 3.75 m.p. (°C) (6.p.) Dens. (g/mL)
Please give detailed answers to the pre and post lab questions. Thank you! NUCLEOPHILIC DISPLACEMENT- FORMATION OF AN ETHER BY AN SN2 REACTION Bond formation by use of an SN2 reaction is very important for organic and biological synthesis. Many new bonds formed make use of this versatile reaction pathway. In this reaction, one partner is the nucleophile and the other partner is the electrophile. The electrophile will have a leaving group that will be lost in the reaction. In...
I did an experiment where I synthesized 2-phenyl-2-propanol using the grignard reaction. please help me answer these lab questions Reagents Moles of Reagent 0.00142 moles (0.224 g)bromobenzene 0.00712 mol (0.173 g) 2 mL of THF (n/a moles) tetrahydrofuran 0.00142 mol (0.083g, 0.11mL) acetone, HPLC grade, anh Reagent Name FW 157.75 24.31 n/a 58 Comments Mg powder grind before using must be anhydrous must be anhydrous Pre-Lab Assignment: 1. Determine the volume (mL) of bromobenzene needed for the experiment. Obtain the...