Question

Drug card for

4. Angiotensin-Converting Enzyme Inhibitors

(-prils)

benazepril (Lotensin)

Answer 1

Answer :

ACE Inhibitors :

Classification :

1. Sulphydryl containing agents : captopril ,is the first ACE inhibitor .

2. Dicarboxylate containing agents : enalapril ,ramipril ,quinapril ,perindopril, lisinopril ,benazepril .

3. Phosphonate containing agents : fosinopril ,trandolapril .

RAMIPRIL :

Uses : it is used to treatment the hypertension , heart failure ,myocardial infarction.

Dose : initial dose is 2.5 mg OD for 1 week ,5 mg OD for next 3 weeks ,then maintenance dose is 10 mg. OD .

Side effects : low blood sugar ,dry cough ,dizziness ,light headed ness ,mouth Try ness ,tired ness ,fatigue ,nausea ,vomiting and diarrhea.

Contraindications : renovascular disease ,severe renal impairment ,volume depleted patients ,hystory of angio edema ,pregnancy and hypotension .

ENALAPRIL :

Uses : management of hypertension ,BP patient with heart failure , post myocardial infarction ,high coronary disease risk .

Dose : initial dose is 5 mg OD , range up to 10 to 40 mg per day

Side effects : low bp , dizziness ,dry cough etc .

Contraindications : hypersensitivity , pregnancy ,children .

CAPTOPRIL :

Uses : hypertension , post myocardial infarction ,congestive cardiac failure .

Dose : 25 mg BD , or 50 Mg tid .

Side effects : cough ,angioedema ,proteinuria , hyperkalemia ,teratogenecity ,acute renal failure ,leukopenia .

Contraindication : hypersensitivity ,stenosis ,renal impairment ,pregnancy .

BENAZEPRIL :

Uses : brand name is lotensin ,it is a medication used to treatment hypertension ,congestive cardiac failure ,chronic renal failure .

Dose : initial dose is 5 mg OD , up to 40 mg / day .

Side effects : cough, Tiredness ,head ache , drowsiness , hypersensitivity .

Contraindicatoons : pregnancy , children .