Question

To answer this question, you may reference the Metabolic Map. Glycogen phosphorylase catalyzes a

  reaction that breaks glycogen. Phosphorylase is one of the enzymes of glycogenolysis that directly generates   In the fasting state, the hormone glucagon   the enzyme, resulting in

  in blood glucose levels.

To answer this question, you may reference the Metabolic Map. Glycogen phosphorylase catalyzes a reaction that breaks -1,4 li

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  • Glycogen phosphorylase catalyzes a phosphorolysis reaction that breaks α-1,4-linkages in glycogen.
    • The rupture of α​​​​​​​-1,4-link occurs at the non-reductive ends of the glycogen structure. The reaction produces one unit of glucose.
  • Phosphorylase is one of the enzymes of glycogenolysis that generates glucose-1-phosphate (G1P)
    • ​​​​​​​A phosphorolysis reaction consist of a bond cleavage by the substitution of a phosphate group. The glucose residue removes by phosphorylase is attacked by a phosphate group to produces the glucose-1-phosphate
  • In the fasting state, the hormone glucagon stimulates/activates the enzyme, resulting in the raising in blood glucose leves
    • This hormone is released by pancreas when the concentration of insulin is two low. The hormone stimulates glycogenolysis in the liver, activating the glycogen phosphorylase to converts the glycogen into glucose which is released in the bloodstream
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