Question

1. Which of the folowing statements about glucokinase and hexokinase (that catalyze the same reaction) is...

1. Which of the folowing statements about glucokinase and hexokinase (that catalyze the same reaction) is TRUE?

A.

Glucokinase has a higher capacity than hexokinase to convert glucose to glucose 6 phosphate

B.

Hexokinase is only active in the liver where it can utilize multiple hexoses

C.

While glucokinase requires ATP for its action, hexokinase requires GTP

D.

Glucokinase can act on multiple glucose-like sugars (such as galactose)

E.

Hexokinase has a higher Km and easily handles all the glucose from a carbohydrate rich meal

2. Which of the following statements about glycogen structure and utilization is FALSE?

A.

Liver glycogen is used to buffer the overall blood glucose level during fasting XX

B.

Glycogen is a polymer of glucose linked by α-1,4 and α-1,6 glycosidic linkages XX

C.

Branched structure of glycogen allows for very rapid mobilization of free glucose monomers when necessary.

D.

Glycogen structure allows compact packing of thousands of glucose molecules together

E.

Eating a large meal promotes the breakdown of glycogen to allow for maximal energy for cells.

3. Which statement about the regulation of insulin and glucagon secretion from the islets of Langerhans is FALSE?

A.

Insulin secretion is adversely affected by high stress.

B.

Both insulin and glucagon are peptides made from longer protein precursors and stored in vesicles to allow for quick release

C.

Insulin and glucagon release occurs together during the fasting state

D.

Alpha and beta cells respond to changes in both the glucose and the amino acid concentrations in the plasma. XX

E.

Alpha and beta cells act as both the sensors and the effectors in this control system

4. In one complete turn of the citric acid (Krebs) cycle:

A.

carbon atoms enter as acetyl~CoA and exit as CO2

B.

carbon atoms from pyruvate are synthesized into a new molecule of glucose

C.

carbon atoms from glucose enter as pyruvate and exit as lactate

D.

carbon atoms from glucose enter as pyruvate and exit as acetyl~CoA

E. carbon atoms from 2 pyruvates combine to form citric acid

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