Question

1. Draw the major product formed from the following elimination reactions. (4 pts) NaOET EtOH, heat 85% H3PO4 १ 80°C heat Y Br + BOKBLOH host + t-BUOKA-BOH EtOH TH + Naget 55°C

Answer 1

MOLOER ETCH major product mecanisme H me 170 The po te N © eliminahan 3 ye Br

H3 Poze 800 mechanisme Hyper Изр- X OH The so callocation 12 са shik 3° с wyka how

I thookL 1 Buolf ا 1 A 7000م مع P)no Mechanisme در اجل

H3 CH₂ HS Not favoured (saytreff's rule) CH3. Stesic hindrance bendronce

4 Hooft Elok 55°C major minor elimination product

BEL NO EH JET substituted product cmajor)

MOLOER ETCH major product mecanisme H me 170 The po te N © eliminahan 3 ye Br
​​1) it is example of E2 eliminateion,The Hydrogen at c1 carbon is not anti to leaving group . The hydrgen at c3 is anti to leaving group Wich abstracts by base and form eliminated product

2) 2 nd example is type of 1-2 methyl shift. OH abstracts proton leave the water molecule form secondary carbocation the methyl group adjucent to carbon shifts and form tertiory carbocation . Forms stable alkene

3)third example Hoffman eliminated product is formed , because of bulky base fos steric hindrance saytzeff eliminated product is not possible

4)in this example simple E2 eliminated product trans is major product

One more product also formed via SN2 reaction gives inverted products